Flatau E, Shneyour A, Hadad N, Shimoni Z
Department of Internal Medicine B, Central Emek Hospital, Afula, Israel.
Isr J Med Sci. 1989 Oct;25(10):553-6.
Positive titers of antibodies against double-stranded (ds) and single-stranded (ss) DNA were found in the sera of 4 and 6 patients, respectively, of 18 who had familial Mediterranean fever (FMF). While anti-dsDNA antibodies were found only in patients with active disease, there was no correlation between the presence of anti-ssDNA antibodies and disease activity. The antibody titers were lower than those found in patients with active systemic lupus erythematosus. This may be due in part to the fact that all the FMF patients were treated with colchicine.
在18例家族性地中海热（FMF）患者中，分别有4例和6例患者血清中检测到抗双链（ds）和单链（ss）DNA抗体阳性。虽然仅在疾病活动期患者中发现抗dsDNA抗体，但抗ssDNA抗体的存在与疾病活动度之间并无关联。这些抗体滴度低于活动性系统性红斑狼疮患者中发现的滴度。这可能部分归因于所有FMF患者均接受了秋水仙碱治疗。
