University of Hull, Hull, UK.
Birmingham City University.
Int J Older People Nurs. 2017 Sep;12(3). doi: 10.1111/opn.12145. Epub 2017 Jan 12.
The aims of this study were to (i) assess the effect of low-cost hygiene and emollient regimens on the skin barrier function (SBF) of people aged >65 year with xerosis (dry skin) on their lower legs; (ii) to assess the utility of portable measures of skin barrier function in terms of stratum corneum hydration (SCH) and transepidermal water loss (TEWL) in community settings; and iii) to provide evidence for a randomised controlled trial on the treatment of adults in a resource-poor country with dry skin on their lower legs which causes and exacerbates the skin disease podoconiosis (non-filarial elephantiasis).
Age increases the risk of impaired skin barrier function which can precipitate skin breakdown. Older skin is frequently characterised by troublesome xerosis and pruritus (itching). Hygiene and emollient practices are central to maintaining skin integrity but are currently under-researched.
A quasi-experimental pilot study of five combinations of cleansing and emollient interventions was applied to the xerotic lower legs of ten participants with no skin disease for five consecutive days. Stratum corneum hydration and transepidermal water loss were measured at baseline and day six. Products were chosen because of effectiveness, low cost and availability in a poor-resource country.
The greatest difference in transepidermal water loss pre-intervention-postintervention was indicated by the regimen of soapy water, 2% glycerine soak and Vaseline (mean 1.14, SD 1.27). This regimen also indicated the greatest difference in stratum corneum hydration (mean 7.92, SD 3.93). The improvement in stratum corneum hydration was significantly greater than for the control (p = .011), soap (p = .050) or water soak (p = .011).
A regimen of washing skin with soapy water, soaking in 2% glycerine for 30 min and applying Vaseline has a beneficial effect on the skin barrier function in older people. The study supports previous findings on the positive effects of glycerine on skin barrier function.
Skin barrier function in older people can be improved using a regimen of washing, soaking in 2% glycerine and applying Vaseline .
本研究旨在：(i) 评估低成本卫生和保湿方案对小腿干性皮肤（皮肤干燥）老年 (>65 岁) 人群皮肤屏障功能 (SBF) 的影响；(ii) 评估便携式皮肤屏障功能测量在社区环境中角质层水分 (SCH) 和经皮水分流失 (TEWL) 的实用性；以及 (iii) 为一项针对资源匮乏国家下肢干性皮肤导致和加剧皮肤疾病 Podoconiosis（非丝虫性象皮病）的成年人的随机对照试验提供证据。
年龄增加皮肤屏障功能受损的风险，这可能导致皮肤破裂。老年人的皮肤经常出现麻烦的干燥和瘙痒（瘙痒）。卫生和保湿措施是保持皮肤完整性的核心，但目前研究不足。
对 10 名无皮肤疾病的参与者的干性小腿进行了为期五天的五种清洁和保湿干预组合的准实验性试点研究。在基线和第六天测量角质层水分和经皮水分流失。选择这些产品是因为它们在资源匮乏国家的有效性、低成本和可用性。
干预前、干预后和干预后的经皮水分流失差异最大的方案是用肥皂水洗、2%甘油浸泡和凡士林(Vaseline)（平均差值为 1.14，标准差为 1.27）。该方案的角质层水分差异最大（平均差值为 7.92，标准差为 3.93）。角质层水分的改善明显大于对照组（p=0.011）、肥皂组（p=0.050）或水浸泡组（p=0.011）。
用肥皂水洗皮肤、浸泡在 2%甘油中 30 分钟并用凡士林(Vaseline)涂抹的方案对老年人的皮肤屏障功能有有益的影响。该研究支持甘油对皮肤屏障功能有积极影响的先前发现。
可以通过使用清洁、浸泡在 2%甘油中并涂抹凡士林(Vaseline)的方案来改善老年人的皮肤屏障功能。
