Herndon David N, Branski Ludwik K
From the *Department of Surgery, The University of Texas Medical Branch, Galveston, TX; and †Shriners Hospitals for Children, Galveston, TX.
Ann Plast Surg. 2017 Feb;78(2 Suppl 1):S9-S10. doi: 10.1097/SAP.0000000000000979.
Partial-thickness burns involve damage to the upper layer of skin, which leaves nerve endings exposed, and therefore represent the most painful of several categories of thermal injuries. Historically, partial-thickness burns were treated conservatively by debriding the blisters, by daily tubbing and washing, and the application of new bandages with topical medications. Human amniotic membrane has been used for centuries as a biological wound dressing. In the past 20 years, there has been an increasing body of literature addressing the use of amniotic tissue in chronic wounds and burns. In this review, we present an overview of the use of amniotic membrane in the treatment of burns including processing methods and early clinical use. We believe that amniotic membranes have great potential in improving burn wound care in the future. Standardized processing methods and terminal sterilization ensure safety and allow the material to be available for use by health care providers around the world in clinical trials and for patient care.
浅度烧伤涉及皮肤上层受损，导致神经末梢外露，因此是几类热损伤中最疼痛的。历史上，浅度烧伤的治疗较为保守，包括清除水疱、每日盆浴和冲洗，以及应用带有局部用药的新绷带。人类羊膜作为生物伤口敷料已使用了几个世纪。在过去20年里，越来越多的文献探讨了羊膜组织在慢性伤口和烧伤治疗中的应用。在本综述中，我们概述了羊膜在烧伤治疗中的应用，包括处理方法和早期临床应用。我们认为羊膜在未来改善烧伤伤口护理方面具有巨大潜力。标准化的处理方法和终端灭菌确保了安全性，并使该材料可供世界各地的医疗保健提供者在临床试验和患者护理中使用。
