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新型牛胶原蛋白膜作为部分厚度烧伤创面敷料的临床应用

Clinical application of new bovine collagen membranes as a partial-thickness burn wound dressing.

作者信息

Sakiel S, Grzybowski J

机构信息

Burn Unit, Municipal Hospital, Siemianowice, Poland.

出版信息

Polim Med. 1995;25(3-4):19-24.

PMID:8610062
Abstract

New bovine collagen membranes were applied for covering of partial-thickness burn wounds to compare with porcine skin used as biological dressing. Forty four of investigated patients had superficial (2a degree), and forty four of them had deep (2b degree) partial thickness burn wounds. When nonperforated collagen membranes or porcine skin were used for dressing of superficial (2a degree) burn wounds, time of healing was established as 11 +/- 3.4 (mean + or - sd) and 12+/- 4.9 days, respectively (n=12). For perforated version of the dressings the time of healing was 9 +/- 3.5 and 10 +/- 3.2, respectively (n=10). The differences were nonsignificant in both cases. When nonperforated collagen membranes or porcine skin were used for treatment of deep (2b degree) burn wounds, the time of healing was established as 29 + or - 6.1 and 30 +/- 5.4 days, respectively ( n=10). The differences were nonsignificant as well. We can conclude from our study that new collagen membranes can be considered as biological dressings and can be recommended for partial-thickness burn wound care. Perforated version of the collagen membranes was better than nonperforated.

摘要

将新型牛胶原膜用于覆盖部分厚度烧伤创面,以与用作生物敷料的猪皮进行比较。44名受调查患者患有浅度(2a度)烧伤,其中44名患有深度(2b度)部分厚度烧伤创面。当使用无孔胶原膜或猪皮来处理浅度(2a度)烧伤创面时,愈合时间分别确定为11±3.4(均值±标准差)天和12±4.9天(n = 12)。对于有孔版本的敷料,愈合时间分别为9±3.5天和10±3.2天(n = 10)。两种情况下差异均无统计学意义。当使用无孔胶原膜或猪皮治疗深度(2b度)烧伤创面时,愈合时间分别确定为29±6.1天和30±5.4天(n = 10)。差异同样无统计学意义。从我们的研究中可以得出结论,新型胶原膜可被视为生物敷料,并可推荐用于部分厚度烧伤创面护理。有孔版本的胶原膜比无孔的更好。

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