Bassetti Matteo, Carnelutti Alessia, Muser Daniele, Righi Elda, Petrosillo Nicola, Di Gregorio Fernando, Werner Thomas J, Alavi Abass
aInfectious Diseases Division, Santa Maria Misericordia University Hospital bCardiovascular Medicine Division, Santa Maria Misericordia University Hospital, Udine cNational Institute for Infectious Diseases Lazzaro Spallanzani-INMI IRCCS, Rome dNuclear Medicine Division, Santa Maria Misericordia University Hospital, Udine, Italy eDivision of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Curr Opin Infect Dis. 2017 Apr;30(2):192-200. doi: 10.1097/QCO.0000000000000354.
18F-Fluorodeoxyglucose positron emission tomography/computed tomography is a well-established technique for diagnosis and management of a number of neoplastic conditions. However, in recent years the body of literature regarding its potential role in infectious diseases has progressively increased, with promising results.
So far 18F-fluorodeoxyglucose positron emission tomography/computed tomography has a well-established role and is recommended by guidelines only in a few settings, such as prosthetic valve endocarditis, vascular device infections, and chronic osteomyelitis. However, even the lack of large, prospective randomized trials, an increasing number of small series and case reports suggest a potential role in the diagnosis, disease staging, and monitoring of treatment response of several other infective conditions.
In this article, we summarize the available evidence and potential future applications of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis and management of infectious diseases.
18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描是一种成熟的技术，用于多种肿瘤疾病的诊断和管理。然而，近年来，关于其在传染病中潜在作用的文献数量逐渐增加，结果令人鼓舞。
到目前为止，18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描已确立了一定作用，仅在少数情况下被指南推荐，如人工瓣膜心内膜炎、血管装置感染和慢性骨髓炎。然而，即使缺乏大型前瞻性随机试验，越来越多的小系列研究和病例报告表明其在其他几种感染性疾病的诊断、疾病分期和治疗反应监测中具有潜在作用。
在本文中，我们总结了18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在传染病诊断和管理中的现有证据及潜在的未来应用。
