罕见的乙胺丁醇诱发的视神经病变：一例报告及文献综述。
The rare ethambutol-induced optic neuropathy: A case-report and literature review.
作者信息
Song Wei, Si Shancheng
机构信息
aDepartment of Ophthalmology, Jiaxing Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, Nanhu District, Jiaxing City, Zhejiang Province bDepartment of Ophthalmology, Beijing Tsinghua Changgung Hospital, Tsinghua University, Changping District, Beijing, China.
出版信息
Medicine (Baltimore). 2017 Jan;96(2):e5889. doi: 10.1097/MD.0000000000005889.
RATIONALE
Ethambutol-induced optic neuropathy (EON) is a well-known complication that results from the use of ethambutol. The ocular manifestations of EON include painless loss of central vision and cecocentral scotomas in the visual field.
PATIENT CONCERNS
A 75-year-old Chinese Han man suffered from this rare ocular disorder because he took ethambutol for about 8 months.
DIAGNOSES
He was diagnosed as EON based on series of ophthalmic examinations performed.
INTERVENTIONS
Since he has stopped taking this drug for 3 months, we just offered some neurotrophic agents to him.
OUTCOMES
One month later, he came back for return visit. The ophthalmic examinations indicated recovery of the visual function very well.
LESSONS
The EON is a reversible optic neuropathy if the ocular toxicity is monitored closely among the tuberculosis patients that take ethambutol.
理论依据
乙胺丁醇所致视神经病变（EON）是使用乙胺丁醇引起的一种众所周知的并发症。EON的眼部表现包括无痛性中心视力丧失和视野中心暗点。
患者情况
一名75岁的中国汉族男性因服用乙胺丁醇约8个月而患上这种罕见的眼部疾病。
诊断
根据所进行的一系列眼科检查，他被诊断为EON。
干预措施
由于他已停药3个月，我们仅给他使用了一些神经营养药物。
结果
1个月后，他回来复诊。眼科检查显示视功能恢复良好。
经验教训
对于服用乙胺丁醇的结核病患者，若密切监测眼部毒性，EON是一种可逆转的视神经病变。
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