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中毒性和营养性视神经病变——最新的小型综述

Toxic and Nutritional Optic Neuropathies-An Updated Mini-Review.

机构信息

Department of Human Anatomy, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.

Department of Forensic Medicine, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.

出版信息

Int J Environ Res Public Health. 2022 Mar 6;19(5):3092. doi: 10.3390/ijerph19053092.

Abstract

Optic neuropathies constitute a group of conditions with various etiologies and might be caused by different factors; we can distinguish the genetic and acquired causes of optic neuropathies. Even though the symptoms are not highly specific, this condition is primarily characterized by unilateral or bilateral vision loss with worsening color detection. The loss may be acute or gradual depending on the causation. In this article, we included a specification of toxic optic neuropathy (TON) mainly triggered by alcohol abuse and also the usage of other substances, including drugs or methanol, as well as intoxication by metals, organic solvents, or carbon dioxide. Nutritional deficiencies, vitamin absorption disorder, and anemia, which usually appear during excessive alcohol intake, and their effect on the etiology of the optic neuropathy have been likewise discussed.

摘要

视神经病变是一组具有多种病因的疾病,可能由不同的因素引起;我们可以区分视神经病变的遗传和获得性原因。尽管症状不是高度特异性的,但这种疾病主要表现为单侧或双侧视力丧失,伴有色觉恶化。根据病因的不同,这种丧失可能是急性的也可能是逐渐的。在本文中,我们特别提到了中毒性视神经病变(TON),主要由酒精滥用引起,也包括其他物质的使用,如药物或甲醇,以及金属、有机溶剂或二氧化碳中毒。同样讨论了营养缺乏、维生素吸收障碍和贫血,这些通常在大量饮酒时出现,以及它们对视神经病变病因的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd33/8910489/ccf59324c9bf/ijerph-19-03092-g001.jpg

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