Crossen P E, Morgan W F
N Z Med J. 1978 Sep 13;88(619):192-5.
Fifty-seven herbicide and pesticide sprayers were studied for the incidence of sister chromatid exchanges (SCEs) in peripheral blood lymphocyte chromosomes. Overall there was no difference between the control group and the sprayers. Five sprayers had an SCE rate three standard deviations outside the mean of the control group. Possible factors contributing to this elevated SCE rate were (1) the failure to use protective clothing and (2) the length of time spraying. Many sprayers failed to take adequate protective measures when mixing and spraying and chemicals were often improperly stored. It is recommended that all persons using herbicides and pesticides take adequate protective measures so that the risk of fatal poisoning and possible long-term genetic hazard be reduced.
对57名除草剂和杀虫剂喷雾器使用者进行了外周血淋巴细胞染色体姐妹染色单体交换（SCEs）发生率的研究。总体而言，对照组和喷雾器使用者之间没有差异。有5名喷雾器使用者的SCE率在对照组平均值之外三个标准差。导致这种SCE率升高的可能因素有：（1）未使用防护服；（2）喷洒时间长度。许多喷雾器使用者在混合和喷洒时未采取充分的防护措施，化学品储存也常常不当。建议所有使用除草剂和杀虫剂的人员采取充分的防护措施，以降低致命中毒风险和可能的长期遗传危害。
