Licciardone J C, Hagan R D, Weiss S, Kaman R L, Taylor S C, Woodworth R M
J Am Osteopath Assoc. 1989 Oct;89(10):1293-4, 1297-301.
The projected incidence of cardiovascular disease (CVD) in male firefighters was determined by the prevalence of current CVD risk factors and the use of the Framingham Study general cardiovascular risk profile in a probability sample of firefighters from two municipal fire departments. Hypercholesterolemia (60.9%) and obesity (56.0%) were the most prevalent risk factors. Significant age-related trends were observed for the prevalence of all CVD risk factors, except glucose intolerance (P = .21) and an abnormal resting electrocardiogram (P = .07). The projected incidence of CVD in firefighters did not differ from that of the general male population (relative risk, 1.0; 95% confidence interval, 0.7 to 1.4); similar risk estimates were observed in age-specific analyses. These findings are in accord with previous incidence and mortality studies that used circulatory diseases as an end point. The present method should be viewed primarily as a hypothesis-generating tool because of its limitations in assessing cause and effect.
通过两个城市消防部门消防员概率样本中当前心血管疾病(CVD)风险因素的患病率以及弗明汉姆研究的一般心血管风险概况,确定男性消防员心血管疾病的预计发病率。高胆固醇血症(60.9%)和肥胖(56.0%)是最普遍的风险因素。除葡萄糖耐量异常(P = 0.21)和静息心电图异常(P = 0.07)外,所有心血管疾病风险因素的患病率均呈现出显著的年龄相关趋势。消防员心血管疾病的预计发病率与一般男性人群无差异(相对风险为1.0;95%置信区间为0.7至1.4);在特定年龄分析中观察到类似的风险估计。这些发现与先前以循环系统疾病为终点的发病率和死亡率研究一致。由于本方法在评估因果关系方面存在局限性,应主要将其视为一种产生假设的工具。