Department of Internal Medicine, Faculty of Medicine, Bahçeşehir University, Göztepe Medical Park Hospital, İstanbul, Turkey.
Department of Medical Microbiology, Faculty of Medicine, Bahçeşehir University, İstanbul, Turkey.
Turk J Med Sci. 2016 Dec 20;46(6):1755-1759. doi: 10.3906/sag-1510-93.
BACKGROUND/AIM: The aim of our study was to determine the usefulness of the Centor score and some basic laboratory tests (complete blood count and C-reactive protein) for the differential diagnosis of exudative tonsillitis due to Group A β-hemolytic streptococcus (GABHS) or due to non-GABHS agents.
The data of clinical and laboratory characteristics of the patients diagnosed with exudative tonsillitis were collected and statistically compared between those having positive GABHS throat culture result and those who were negative for any bacterial agent.
Totally 899 adult patients were included in our study; 56 (6.2%) of them were positive for GABHS, while 34 (3.8%) of the cases had a bacterial cause other than GABHS. The remaining 809 (90%) were accepted as non-GABHS cases. The percentages of patients having Centor score of 3 or greater, neutrophilia, lymphocytopenia, and CRP values of greater than 5-fold normal upper reference range were significantly higher in GABHS patients.
Centor score of 3 or more together with high CRP, neutrophilia, and lymphocytopenia is predictive for GABHS tonsillopharyngitis.
背景/目的：本研究旨在确定 Centor 评分和一些基本实验室检查（全血细胞计数和 C 反应蛋白）在鉴别由 A 组β-溶血性链球菌（GABHS）或非 GABHS 病原体引起的渗出性扁桃体炎中的作用。
收集了诊断为渗出性扁桃体炎的患者的临床和实验室特征数据，并对 GABHS 咽拭子培养阳性和任何细菌阴性的患者进行了统计学比较。
共有 899 例成年患者纳入本研究；其中 56 例（6.2%）为 GABHS 阳性，34 例（3.8%）为 GABHS 以外的细菌病原体。其余 809 例（90%）被认为是非 GABHS 病例。GABHS 患者的 Centor 评分≥3 分、中性粒细胞增多、淋巴细胞减少和 CRP 值高于正常上限 5 倍的患者比例显著更高。
Centor 评分≥3 分伴高 CRP、中性粒细胞增多和淋巴细胞减少提示 GABHS 扁桃体咽炎。
