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[A组β溶血性链球菌在儿童及青少年咽部急性炎症性病变病因学中的作用]

[The role of group A β-hemolytic streptococcus in the etiology of acute inflammatory pathology of the pharynx in children and adolescents].

作者信息

Evsikova M M, Radtsig E Yu, Varavina M A

机构信息

Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Department of Otolaryngology of Pediatric Faculty, Moscow, Russia, 117997.

出版信息

Vestn Otorinolaringol. 2020;85(1):22-24. doi: 10.17116/otorino20208501122.

DOI:10.17116/otorino20208501122
PMID:32241983
Abstract

UNLABELLED

Group A β-hemolytic streptococcus (GABHS) is the most important bacterial agent in the genesis of acute inflammatory conditions of the pharynx due to the possible development of local and systemic complications. During the seasonal increase of incidence of respiratory viral infections, the possibility of viral-bacterial co-infection is often not taken into account.

AIM

Determine the incidence of GABHS in children with catarrhal symptoms (rhinorrhea, cough) and without them.

MATERIAL AND METHODS

69 children with signs of acute tonsillopharyngitis (ATP) in the first 2 days of the disease were examined. Patients were divided into 2 groups depending on the presence or absence of rhinorrhea and cough. All patients underwent a comprehensive otorhinolaryngological examination and bacteriological examination of smears from the surface of the posterior pharyngeal wall and lacunae of the tonsils. Obtained data was processed by basic statistical methods.

RESULTS

Incidence of GABHS in children with ATP without catarrhal symptoms was 9.5%, with rhinorrhea and cough - 3.7%. Median age for the detection of GABHS in patients with ATP was 5.6 years. A statistically significant symptom of GABHS-positive patients in our study was the enlargement of the anterior cervical lymph nodes; plaques on the tonsils were found only in 20% of cases.

CONCLUSION

GABHS is predominant in patients with ATP without catarrhal phenomena, however, the presence of rhinorrhea and coughing in a patient does not exclude the possibility of the presence of GABHS infection, therefore, patients with ATP should undergo an objective examination for GABHS.

摘要

未标注

A组β溶血性链球菌(GABHS)是咽部急性炎症性疾病发生中最重要的细菌病原体,因为可能会出现局部和全身并发症。在呼吸道病毒感染发病率季节性上升期间,病毒 - 细菌合并感染的可能性常常未被考虑到。

目的

确定有卡他症状(流涕、咳嗽)和无卡他症状的儿童中GABHS的发病率。

材料与方法

对69例在疾病发作头2天出现急性扁桃体咽炎(ATP)体征的儿童进行检查。根据是否存在流涕和咳嗽将患者分为2组。所有患者均接受了全面的耳鼻喉科检查以及咽后壁表面和扁桃体隐窝涂片的细菌学检查。所得数据采用基本统计方法进行处理。

结果

无卡他症状的ATP患儿中GABHS的发病率为9.5%,有流涕和咳嗽症状的为3.7%。ATP患者中检测到GABHS的中位年龄为5.6岁。在我们的研究中,GABHS阳性患者具有统计学意义的症状是颈前淋巴结肿大;仅20%的病例在扁桃体上发现斑块。

结论

GABHS在无卡他现象的ATP患者中占主导地位,然而,患者出现流涕和咳嗽并不排除存在GABHS感染的可能性,因此,ATP患者应接受GABHS的客观检查。

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