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宿主间传播的肺炎链球菌——一段有毒关系的新牺牲品。

Host-to-Host Transmission of the Pneumococcus-New Victims of a Toxic Relationship.

机构信息

Research Centre for Infectious Diseases, Department of Molecular and Cellular Biology, University of Adelaide, Adelaide 5005, Australia.

Research Centre for Infectious Diseases, Department of Molecular and Cellular Biology, University of Adelaide, Adelaide 5005, Australia.

出版信息

Cell Host Microbe. 2017 Jan 11;21(1):5-6. doi: 10.1016/j.chom.2016.12.011.

DOI:10.1016/j.chom.2016.12.011
PMID:28081444
Abstract

Host-to-host transmission is critical for survival of the human-adapted bacterium Streptococcus pneumoniae. In this issue of Cell Host & Microbe, Zafar et al. (2017) show that transmission is dependent on nasopharyngeal inflammation elicited by the toxin pneumolysin, causing increased shedding and enhanced survival of the bacterium in the environment.

摘要

宿主间传播对于适应人类的肺炎链球菌的存活至关重要。在本期《细胞宿主与微生物》中，Zafar 等人（2017 年）表明，传播依赖于由毒素肺炎球菌溶血素引起的鼻咽部炎症，导致细菌在环境中的脱落增加和存活能力增强。

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