The effect of slime production on vancomycin efficacy in the treatment of experimental endocarditis due to Staphylococcus epidermidis.
作者信息
Baddour L M, Christensen G D, Schadow K H
机构信息
Department of Medicine, University of Tennessee, Memphis.
出版信息
J Antimicrob Chemother. 1989 Sep;24(3):365-73. doi: 10.1093/jac/24.3.365.
PMID:2808192
Abstract
We compared the efficacy of vancomycin in the treatment of experimental endocarditis caused by either a parent strain of Staphylococcus epidermidis that produced slime or a daughter strain that produced less slime. After subcutaneously administered vancomycin, we noted similar cure rates and similar microbiological characteristics of endocardial infections in rats challenged with these strains, regardless of slime produced.
摘要
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