结核分枝杆菌TB282和TB284的全基因组序列，分别为一种广泛传播的菌株和一种独特的菌株，在美国加利福尼亚州洛杉矶市中心先前的一项结核病传播研究中被鉴定出来。
Whole-Genome Sequences of Mycobacterium tuberculosis TB282 and TB284, a Widespread and a Unique Strain, Respectively, Identified in a Previous Study of Tuberculosis Transmission in Central Los Angeles, California, USA.
作者信息
Zhang Lixin, Yang Zhenhua
机构信息
Department of Epidemiology & Biostatistics, Michigan State University, East Lansing, Michigan, USA
Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
出版信息
Genome Announc. 2017 Jan 12;5(2):e01418-16. doi: 10.1128/genomeA.01418-16.
Abstract
We report here the genome sequences of two Mycobacterium tuberculosis clinical isolates previously identified in central Los Angeles, CA, in the 1990s using a PacBio platform. Isolate TB282 represents a large-cluster strain that caused 27% of the tuberculosis cases, while TB284 represents a strain that caused disease in only one patient.
摘要
我们在此报告两株结核分枝杆菌临床分离株的基因组序列，这两株菌于20世纪90年代在加利福尼亚州洛杉矶市中心首次鉴定，采用的是PacBio平台。分离株TB282代表一株大簇菌株，引发了27%的结核病病例，而TB284代表一株仅在一名患者中引发疾病的菌株。
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