RahimiRad Shaghayegh, Alizadeh Ali, Alizadeh Effat, Hosseini Seyyed Masoud
Student of Medicine, Tuberclosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Urmia, Iran.
Department of English, Urmia University, Urmia, Iran.
J Res Med Sci. 2016 Jul 29;21:51. doi: 10.4103/1735-1995.187253. eCollection 2016.
The avian influenza subtype H9N2 is considered a low pathogenic virus which is endemic in domestic poultry of a majority of Asian countries. Many reports of seropositivity in occupationally poultry-exposed workers and a number of confirmed human infections with an H9N2 subtype of avian influenza have been documented up to now. Recently, the human infections with both H7N9 and H10N8 viruses highlighted that H9N2 has a great potential for taking a part in the emergence of new human-infecting viruses. This review aimed at discussing the great potential of H9N2 virus which is circulating at avian-human interface, for cross-species transmission, contribution in the production of new reassortants and emergence of new pandemic subtypes. An intensified surveillance is needed for controlling the future risks which would be created by H9N2 circulation at avian-human interfaces.
禽流感H9N2亚型被认为是一种低致病性病毒，在大多数亚洲国家的家禽中呈地方流行性。到目前为止，已有许多关于职业性接触家禽的工人血清阳性的报告，以及一些人感染H9N2亚型禽流感的确诊病例。最近，人类感染H7N9和H10N8病毒凸显出H9N2在新型人类感染病毒出现过程中具有很大潜力。本综述旨在探讨在禽-人界面传播的H9N2病毒在跨物种传播、产生新的重配病毒和出现新的大流行亚型方面的巨大潜力。需要加强监测，以控制H9N2在禽-人界面传播所带来的未来风险。
