Mohamed Shaaban K, Marzouk Adel A, Albayati Mustafa R, Abdelhamid Antar A, Simpson Jim
Faculty of Science and Engineering, Health Care Division, Manchester Metropolitan University, Manchester M1 5GD, England; Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al Azhar University, 71515 Assiut, Egypt.
Acta Crystallogr E Crystallogr Commun. 2017 Jan 1;73(Pt 1):59-62. doi: 10.1107/S2056989016019332.
The title compound, CHClNO, crystallizes with two unique mol-ecules in the asymmetric unit. In each mol-ecule, the central imidazole ring is substituted at the 2-, 4- and 5-positions by benzene rings. The 2-substituted ring carries a Cl atom at the 4-position. One of the imidazole N atoms in each mol-ecule has a propan-2-ol substituent. In the crystal, a series of O-H⋯N, C-H⋯O and C-H⋯Cl hydrogen bonds, augmented by several C-H⋯π(ring) inter-actions, generate a three-dimensional network of mol-ecules stacked along the -axis direction.
标题化合物CHClNO在不对称单元中结晶出两个独特的分子。在每个分子中，中心咪唑环在2、4和5位被苯环取代。2-取代环在4位带有一个Cl原子。每个分子中的一个咪唑N原子带有一个丙-2-醇取代基。在晶体中，一系列O-H⋯N、C-H⋯O和C-H⋯Cl氢键，再加上几个C-H⋯π(环)相互作用，形成了沿z轴方向堆叠的分子三维网络。
