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1-[2-(4-氯苯基)-4,5-二苯基-1-咪唑-1-基]丙-2-醇的晶体结构

Crystal structure of 1-[2-(4-chloro-phen-yl)-4,5-diphenyl-1-imidazol-1-yl]propan-2-ol.

作者信息

Mohamed Shaaban K, Marzouk Adel A, Albayati Mustafa R, Abdelhamid Antar A, Simpson Jim

机构信息

Faculty of Science and Engineering, Health Care Division, Manchester Metropolitan University, Manchester M1 5GD, England; Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al Azhar University, 71515 Assiut, Egypt.

出版信息

Acta Crystallogr E Crystallogr Commun. 2017 Jan 1;73(Pt 1):59-62. doi: 10.1107/S2056989016019332.

Abstract

The title compound, CHClNO, crystallizes with two unique mol-ecules in the asymmetric unit. In each mol-ecule, the central imidazole ring is substituted at the 2-, 4- and 5-positions by benzene rings. The 2-substituted ring carries a Cl atom at the 4-position. One of the imidazole N atoms in each mol-ecule has a propan-2-ol substituent. In the crystal, a series of O-H⋯N, C-H⋯O and C-H⋯Cl hydrogen bonds, augmented by several C-H⋯π(ring) inter-actions, generate a three-dimensional network of mol-ecules stacked along the -axis direction.

摘要

标题化合物CHClNO在不对称单元中结晶出两个独特的分子。在每个分子中,中心咪唑环在2、4和5位被苯环取代。2-取代环在4位带有一个Cl原子。每个分子中的一个咪唑N原子带有一个丙-2-醇取代基。在晶体中,一系列O-H⋯N、C-H⋯O和C-H⋯Cl氢键,再加上几个C-H⋯π(环)相互作用,形成了沿z轴方向堆叠的分子三维网络。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144a/5209773/fd756f9f41e9/e-73-00059-fig1.jpg

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