Moore Melinda, Eiseman Elisa, Fisher Gail, Olmsted Stuart S, Sama Preethi R, Zambrano John A
Rand Health Q. 2012 Jun 1;2(2):3. eCollection 2012 Summer.
The Army manages the Department of Defense Serum Repository (DoDSR) of over 43 million serum samples and the associated Defense Medical Surveillance System (DMSS) database that links individual service member characteristics to these biological samples. The main mission and use of these resources has been for military health surveillance. The Army turned to RAND Arroyo Center to systematically examine current requirements and capabilities of the DoDSR and DMSS, identify gaps, and suggest strategies to improve their ability to meet current and potential future military health needs, including surveillance, outbreak investigation, research, and clinical support, particularly as these relate to influenza and other infectious disease threats. The research drew information from written documents and interviews with military and civilian experts. The study identified a number of opportunities to improve the management, content, and use of the serum repository and associated database. There were six main recommendations: (1) clarify and communicate the missions of the DoDSR and DMSS both within and beyond the Department of Defense; (2) empower, structure, and resource the organizational oversight of DoDSR and DMSS so that they can fulfill the full range of their missions; (3) create an integrative data plan for comprehensive health surveillance; (4) enhance the utility of specimens; (5) plan for the next repository facility; and (6) raise awareness of and expand access to DoDSR and DMSS.
美国陆军管理着国防部血清库（DoDSR），该血清库拥有超过4300万份血清样本，以及相关的国防医疗监测系统（DMSS）数据库，该数据库将现役军人的个人特征与这些生物样本相链接。这些资源的主要任务和用途一直是用于军事健康监测。美国陆军求助于兰德阿罗约中心，以系统地审查DoDSR和DMSS的当前要求和能力，找出差距，并提出战略建议，以提高它们满足当前和未来潜在军事健康需求的能力，包括监测、疫情调查、研究和临床支持，特别是与流感和其他传染病威胁相关的需求。该研究从书面文件以及对军事和 civilian experts（此处疑有误，推测可能是civilian experts，即文职专家）的访谈中获取信息。该研究确定了一些改善血清库及相关数据库管理、内容和用途的机会。有六项主要建议：（1）在国防部内外明确并传达DoDSR和DMSS的任务；（2）赋予DoDSR和DMSS组织监督权力、构建其架构并提供资源，以便它们能够履行全部任务；（3）制定综合健康监测的综合数据计划；（4）提高样本的效用；（5）规划下一个储存库设施；（6）提高对DoDSR和DMSS的认识并扩大其访问范围。
