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IgG4相关性垂体炎:病例报告及文献综述

IgG4-Related Hypophysitis: Case Report and Literature Review.

作者信息

Decker Lauren, Crawford Angela M, Lorenzo Gamaliel, Stippler Martina, Konstantinov Konstantin N, SantaCruz Karen

机构信息

Pathology, University of New Mexico School of Medicine, Albuquerque, New Mexico.

Department of Surgery, University of Maryland.

出版信息

Cureus. 2016 Dec 1;8(12):e907. doi: 10.7759/cureus.907.

DOI:10.7759/cureus.907
PMID:28083451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5208633/
Abstract

IgG4-related hypophysitis is a rare, inflammatory process of the pituitary that mimics more commonly seen pituitary tumors. We report a case of IgG4-related hypophysitis in a 16-year-old female with diabetes insipidus who was found to have IgG4-related hypophysitis based on tissue diagnosis. This entity has not been previously described in a pediatric patient. Recognition of certain inflammatory processes of the pituitary may lead to alternative means of diagnosis and medical management without a biopsy.

摘要

IgG4相关性垂体炎是一种罕见的垂体炎症性疾病,可模仿更常见的垂体肿瘤。我们报告一例16岁患有尿崩症的女性IgG4相关性垂体炎病例,该病例经组织诊断确诊。此前尚未有儿科患者患此病的报道。认识到垂体的某些炎症过程可能会带来无需活检的其他诊断方法和药物治疗手段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e7/5208633/82c6ed9cd70c/cureus-0008-00000000907-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e7/5208633/d126bdebfaf6/cureus-0008-00000000907-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e7/5208633/82c6ed9cd70c/cureus-0008-00000000907-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e7/5208633/d126bdebfaf6/cureus-0008-00000000907-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e7/5208633/82c6ed9cd70c/cureus-0008-00000000907-i02.jpg

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Pituitary. 2015 Oct;18(5):722-30. doi: 10.1007/s11102-015-0650-9.
2
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Endocrinol Diabetes Metab Case Rep. 2014;2014:140062. doi: 10.1530/EDM-14-0062. Epub 2014 Sep 1.
3
Autoimmune hypophysitis presenting with intracranial multi-organ involvement: three case reports and review of the literature.
AACE Clin Case Rep. 2024 Jul 15;10(5):202-205. doi: 10.1016/j.aace.2024.07.004. eCollection 2024 Sep-Oct.
4
Increased Serum-Immunoglobulin G4 Levels in a 12-Year-Old Male Patient With Central Diabetes Insipidus.一名12岁中枢性尿崩症男性患者血清免疫球蛋白G4水平升高。
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5
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6
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Int J Endocrinol. 2019 Dec 18;2019:5382640. doi: 10.1155/2019/5382640. eCollection 2019.
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