Patil Rohit V, Woldu Solomon L, Lucas Elena, Quinn Andrew M, Francis Franto, Margulis Vitaly
George Washington University, Department of Urology, Washington DC, USA.
University of Texas Southwestern Medical Center, Department of Urology, Dallas, TX, USA.
Urol Case Rep. 2017 Jan 10;11:33-36. doi: 10.1016/j.eucr.2016.10.017. eCollection 2017 Feb.
A 49-year-old Caucasian woman presented to the dermatology clinic for follow-up of malignant melanoma with a complaint of painless gross hematuria. Two years prior she was diagnosed with malignant melanoma from a skin lesion on her left flank treated with wide excision, negative axillary sentinel lymph node biopsy, and adjuvant radiotherapy. Subsequently, she had no evidence of disease until urologic evaluation of her hematuria revealed two lesions in her bladder and cytopathology demonstrated findings consistent with malignant melanoma. We review literature on melanoma metastatic to the bladder and discuss the potential role of metastasectomy and other treatment strategies in such rare cases.
一名49岁的白种女性因无痛肉眼血尿前往皮肤科诊所进行恶性黑色素瘤的随访。两年前，她因左侧胁腹的皮肤病变被诊断为恶性黑色素瘤，接受了广泛切除、腋窝前哨淋巴结活检阴性及辅助放疗。此后，她一直没有疾病迹象，直到对其血尿进行泌尿科评估时发现膀胱有两个病变，细胞病理学检查结果显示与恶性黑色素瘤一致。我们回顾了关于黑色素瘤转移至膀胱的文献，并讨论了在这种罕见病例中转移灶切除术和其他治疗策略的潜在作用。
