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黑色素瘤转移至膀胱:一例报告。

Melanoma metastasis to the bladder: A case report.

作者信息

Kumar Raj A, Batra Nikhil, Frankel Jon, Kumar Udaya

机构信息

Catherine & Joseph Aresty Department of Urology, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.

Department of Urology, University of Florida College of Medicine, University of Florida, Gainesville, FL, USA.

出版信息

Urol Case Rep. 2021 Nov 9;40:101941. doi: 10.1016/j.eucr.2021.101941. eCollection 2022 Jan.

DOI:10.1016/j.eucr.2021.101941
PMID:34820290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8601986/
Abstract

Metastasis of malignant melanoma to the bladder is rarely seen clinically with only 29 cases reported in English-language literature. However, autopsy series of melanoma patients have shown that metastasis to the bladder could be as high as 37%, implying that numerous cases remain undiagnosed. This report details a case of malignant melanoma metastasis to the bladder. Patient presented with severe anemia and history of gross hematuria. Computerized tomography (CT) revealed a 2.7 cm mass in the bladder. Cystoscopy confirmed presence of a mass. Patient underwent cystoscopy and transurethral resection of the tumor, revealed to be melanoma on pathology.

摘要

恶性黑色素瘤转移至膀胱在临床上很少见,英文文献中仅报道了29例。然而,黑色素瘤患者的尸检系列显示,膀胱转移率可能高达37%,这意味着许多病例仍未被诊断出来。本报告详细介绍了一例恶性黑色素瘤转移至膀胱的病例。患者表现为严重贫血和肉眼血尿病史。计算机断层扫描(CT)显示膀胱内有一个2.7厘米的肿块。膀胱镜检查证实有肿块存在。患者接受了膀胱镜检查和经尿道肿瘤切除术,病理检查显示为黑色素瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4162/8601986/d980e7e48377/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4162/8601986/d980e7e48377/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4162/8601986/d980e7e48377/gr1.jpg

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引用本文的文献

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Metastatic Melanoma to the Urinary Bladder: A Rare Cause of Visible Haematuria.膀胱转移性黑色素瘤:肉眼血尿的罕见原因。
Case Rep Urol. 2024 Mar 1;2024:5516547. doi: 10.1155/2024/5516547. eCollection 2024.

本文引用的文献

1
United States burden of melanoma and non-melanoma skin cancer from 1990 to 2019.美国 1990 年至 2019 年黑色素瘤和非黑色素瘤皮肤癌负担。
J Am Acad Dermatol. 2021 Aug;85(2):388-395. doi: 10.1016/j.jaad.2021.03.109. Epub 2021 Apr 20.
2
Surgery of metastatic melanoma after systemic therapy - the SUMMIST trial: study protocol for a randomized controlled trial.全身治疗后转移性黑色素瘤的手术——SUMMIST试验:一项随机对照试验的研究方案
Acta Oncol. 2021 Jan;60(1):52-55. doi: 10.1080/0284186X.2020.1846213. Epub 2020 Nov 30.
3
Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001.
KEYNOTE-001 研究中接受派姆单抗治疗的晚期黑色素瘤患者的 5 年生存结果。
Ann Oncol. 2019 Apr 1;30(4):582-588. doi: 10.1093/annonc/mdz011.
4
Metastatic Melanoma to the Bladder: Case Report and Review of the Literature.膀胱转移性黑色素瘤:病例报告及文献综述
Urol Case Rep. 2017 Jan 10;11:33-36. doi: 10.1016/j.eucr.2016.10.017. eCollection 2017 Feb.
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Malignant melanoma of the genitourinary tract.泌尿生殖道恶性黑色素瘤。
J Urol. 1984 Nov;132(5):859-68. doi: 10.1016/s0022-5347(17)49927-7.