Cryo-EM structure of Nma111p, a unique HtrA protease composed of two protease domains and four PDZ domains.
作者信息
Zhang Li, Wang Xiaojing, Fan Fenghui, Wang Hong-Wei, Wang Jiawei, Li Xueming, Sui Sen-Fang
机构信息
State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
出版信息
Cell Res. 2017 Apr;27(4):582-585. doi: 10.1038/cr.2017.5. Epub 2017 Jan 13.
Abstract
摘要
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Characterization of the structure and function of Escherichia coli DegQ as a representative of the DegQ-like proteases of bacterial HtrA family proteins.鉴定大肠杆菌 DegQ 作为细菌 HtrA 家族蛋白 DegQ 样蛋白酶的代表性成员的结构和功能。
Structure. 2011 Sep 7;19(9):1328-37. doi: 10.1016/j.str.2011.06.013.
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Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.DegQ 蛋白酶的分子适应在细菌细胞包膜中发挥蛋白质质量控制作用。
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