[一名75岁高输出量回肠造口术女性患者的急性肾衰竭]

[Acute renal failure in a 75-year-old woman with a high-output ileostoma].

作者信息

Teege S, Wiech T, Steinmetz O M

机构信息

III. Medizinische Klinik, Abteilung Nephrologie, Zentrum für Innere Medizin, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.

Institut für Pathologie, Sektion Nephropathologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.

出版信息

Internist (Berl). 2017 May;58(5):507-511. doi: 10.1007/s00108-016-0175-y.

DOI:10.1007/s00108-016-0175-y

PMID:28084501

Abstract

We report on a 75-year old woman who presented with acute oliguric renal failure. The kidney biopsy revealed calcium oxalate depositions in the tubular lumen, caused by an overload of intravenous ascorbic acid (cumulative dose of 240 g). Due to a lack of specific therapeutic interventions, the patient remained dialysis-dependent. Iatrogenic causes of kidney failure play an important role in the pathogenesis of kidney diseases and should always be considered in patients with acute renal failure. Detailed evaluation of the patient history is often suggestive, while renal biopsy can establish the diagnosis.

摘要

我们报告了一位75岁的女性，她出现了急性少尿性肾衰竭。肾脏活检显示肾小管腔内有草酸钙沉积，这是由静脉注射维生素C过量（累积剂量240克）所致。由于缺乏特定的治疗干预措施，该患者一直依赖透析。医源性肾衰竭病因在肾脏疾病的发病机制中起重要作用，对于急性肾衰竭患者应始终予以考虑。详细评估患者病史往往具有提示作用，而肾活检可明确诊断。