Topal Kubra, Aktan Bulent, Sakat Muhammed Sedat, Kilic Korhan, Gozeler Mustafa Sitki
a Department of Otorhinolaryngology , Training and Research Hospital , Erzurum , Turkey.
b Faculty of Medicine, Department of Otorhinolaryngology , Ataturk University , Erzurum , Turkey.
Acta Otolaryngol. 2017 Jun;137(6):618-622. doi: 10.1080/00016489.2016.1269945. Epub 2017 Jan 13.
Tramadol was found to be more effective than dexamethasone in post-operative pain control, with long-lasting relief of pain.
This study aimed to compare the effects of pre-operative local injections of tramadol and dexamethasone on post-operative pain, nausea and vomiting in patients who underwent tonsillectomy.
Sixty patients between 3-13 years of age who were planned for tonsillectomy were included in the study. Patients were divided into three groups. Group 1 was the control group. Patients in Group 2 received 0.3 mg/kg Dexamethasone and Group 3 received 0.1 mg/kg Tramadol injection to the peritonsillary space just before the operation. Patients were evaluated for nausea, vomiting, and pain.
When the control and the dexamethasone groups were compared; there were statistically significant differences in pain scores at post-operative 15 and 30 min, whereas there was no statistically significant difference in pain scores at other hours. When the control and tramadol groups were compared, there was a statistically significant difference in pain scores at all intervals. When tramadol and dexamethasone groups were compared, there was no statistically significant difference in pain scores at post-operative 15 and 30 min, 1 and 2 h, whereas there was a statistically significant difference in pain scores at post-operative 6 and 24 h.
发现曲马多在术后疼痛控制方面比地塞米松更有效，能长期缓解疼痛。
本研究旨在比较术前局部注射曲马多和地塞米松对扁桃体切除术后患者疼痛、恶心和呕吐的影响。
纳入60例计划行扁桃体切除术的3至13岁患者。患者分为三组。第1组为对照组。第2组患者在手术前接受0.3mg/kg地塞米松，第3组患者在手术前接受0.1mg/kg曲马多注射至扁桃体周围间隙。对患者的恶心、呕吐和疼痛情况进行评估。
比较对照组和地塞米松组时，术后15分钟和30分钟的疼痛评分有统计学显著差异，而其他时间的疼痛评分无统计学显著差异。比较对照组和曲马多组时，所有时间段的疼痛评分均有统计学显著差异。比较曲马多组和地塞米松组时，术后15分钟和30分钟、1小时和2小时的疼痛评分无统计学显著差异，而术后6小时和24小时的疼痛评分有统计学显著差异。
