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一种用于选择疣治疗方法的专家系统。

An expert system for selecting wart treatment method.

作者信息

Khozeimeh Fahime, Alizadehsani Roohallah, Roshanzamir Mohamad, Khosravi Abbas, Layegh Pouran, Nahavandi Saeid

机构信息

Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Computer Engineering, Sharif University of Technology, Azadi Ave, Tehran, Iran.

出版信息

Comput Biol Med. 2017 Feb 1;81:167-175. doi: 10.1016/j.compbiomed.2017.01.001. Epub 2017 Jan 6.

Abstract

As benign tumors, warts are made through the mediation of Human Papillomavirus (HPV) and may grow on all parts of body, especially hands and feet. There are several treatment methods for this illness. However, none of them can heal all patients. Consequently, physicians are looking for more effective and customized treatments for each patient. They are endeavoring to discover which treatments have better impacts on a particular patient. The aim of this study is to identify the appropriate treatment for two common types of warts (plantar and common) and to predict the responses of two of the best methods (immunotherapy and cryotherapy) to the treatment. As an original work, the study was conducted on 180 patients, with plantar and common warts, who had referred to the dermatology clinic of Ghaem Hospital, Mashhad, Iran. In this study, 90 patients were treated by cryotherapy method with liquid nitrogen and 90 patients with immunotherapy method. The selection of the treatment method was made randomly. A fuzzy logic rule-based system was proposed and implemented to predict the responses to the treatment method. It was observed that the prediction accuracy of immunotherapy and cryotherapy methods was 83.33% and 80.7%, respectively. According to the results obtained, the benefits of this expert system are multifold: assisting physicians in selecting the best treatment method, saving time for patients, reducing the treatment cost, and improving the quality of treatment.

摘要

作为良性肿瘤,疣是由人乳头瘤病毒(HPV)介导形成的,可生长在身体的各个部位,尤其是手和脚。这种疾病有几种治疗方法。然而,没有一种方法能治愈所有患者。因此,医生们正在为每个患者寻找更有效且个性化的治疗方法。他们致力于发现哪种治疗方法对特定患者有更好的效果。本研究的目的是确定两种常见类型疣(跖疣和寻常疣)的合适治疗方法,并预测两种最佳治疗方法(免疫疗法和冷冻疗法)的治疗反应。作为一项原创研究,该研究对180名患有跖疣和寻常疣的患者进行,这些患者均前往伊朗马什哈德加姆医院皮肤科诊所就诊。在本研究中,9名患者采用液氮冷冻疗法治疗,90名患者采用免疫疗法治疗。治疗方法的选择是随机进行的。提出并实施了一个基于模糊逻辑规则的系统来预测对治疗方法的反应。结果发现,免疫疗法和冷冻疗法的预测准确率分别为83.33%和80.7%。根据所得结果,该专家系统有诸多益处:协助医生选择最佳治疗方法、为患者节省时间、降低治疗成本以及提高治疗质量。

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