妊娠合并登革热感染及其对胎盘的影响。
Dengue infection in pregnancy and its impact on the placenta.
机构信息
Departamento Materno-infantil, Universidade Federal Fluminense, 303, Marquês do Paraná Street, 3° floor, Centro, Niterói, Rio de Janeiro 24033-900, Brazil.
Department of Pathology, Universidade Federal Fluminense, 303, Marquês do Paraná Street, Centro, Niterói, Rio de Janeiro, 24033-900, Brazil.
出版信息
Int J Infect Dis. 2017 Feb;55:109-112. doi: 10.1016/j.ijid.2017.01.002. Epub 2017 Jan 11.
A histopathological and immunohistochemical study was conducted in placental tissues and retained products of conception from 24 patients with confirmed dengue infection during pregnancy. The immunohistochemical assay was positive for dengue virus in 19 placental and three ovular remnants analyzed. The light microscopic findings were signs of hypoxia, choriodeciduitis, deciduitis and intervillositis and the viral antigens were found in cytoplasmic of the trophoblast, villous stroma and decidua. Our results suggest that immunohistochemistry could be used as a laboratory confirmation method for dengue in pregnant women, especially in endemic areas when embedded material is the only material available.
对 24 例确诊妊娠期登革热感染患者的胎盘组织和残留产物进行了组织病理学和免疫组织化学研究。对 19 例胎盘和 3 例卵黄囊残片进行的免疫组化检测均呈登革病毒阳性。光镜下可见缺氧、绒毛膜绒毛膜炎、蜕膜炎和绒毛膜炎的表现，病毒抗原存在于滋养细胞、绒毛间质和蜕膜的细胞质中。我们的结果表明，免疫组化可作为孕妇登革热的实验室确诊方法，尤其是在流行地区，当唯一可用的材料是嵌入材料时。
Zotero 插件