抗结核海洋天然产物。
Antitubercular Marine Natural Products.
机构信息
Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Jilin Provincial Academy of Chinese Medicine Sciences, Changchun 130021, China.
出版信息
Curr Med Chem. 2018;25(20):2304-2328. doi: 10.2174/0929867324666170113120221.
Due to the importance of nature as a source of new drug candidates, the purpose of this article is to emphasize the marine natural products, which exhibit antitubercular activity, published between January 2000 and May 2016, with 138 quotations to 250 compounds obtained from marine resources. These metabolites are organized by chemical constitution and named as simple alkyl lipids derivatives, aromatics derivatives, peptides, alkaloids, terpenoids, steroids, macrolides, and polycyclic polyketides.
由于自然是新药物候选物的重要来源，本文的目的是强调海洋天然产物，这些产物具有抗结核活性，发表于 2000 年 1 月至 2016 年 5 月之间，从海洋资源中获得了 138 个引文和 250 个化合物。这些代谢物按化学结构分类，分别命名为简单烷基脂质衍生物、芳烃衍生物、肽、生物碱、萜类、甾体、大环内酯和多环聚酮。
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