来自海洋微生物的糖基化天然产物。
Glycosylated Natural Products From Marine Microbes.
作者信息
Li Kunlong, Cai Jian, Su Ziqi, Yang Bin, Liu Yonghong, Zhou Xuefeng, Huang Jingxia, Tao Huaming
机构信息
CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.
College of Earth and Planetary Sciences, University of Chinese Academy of Sciences, Beijing, China.
出版信息
Front Chem. 2020 Jan 10;7:879. doi: 10.3389/fchem.2019.00879. eCollection 2019.
A growing body of evidence indicates that glycosylated natural products have become vital platforms for the development of many existing first-line drugs. This review covers 205 new glycosides over the last 22 years (1997-2018), from marine microbes, including bacteria, cyanobacteria, and fungi. Herein, we discuss the structures and biological activities of these compounds, as well as the details of their source organisms.
越来越多的证据表明，糖基化天然产物已成为许多现有一线药物开发的重要平台。本综述涵盖了过去22年（1997 - 2018年）从海洋微生物（包括细菌、蓝细菌和真菌）中发现的205种新糖苷。在此，我们讨论了这些化合物的结构和生物活性，以及它们来源生物的详细信息。
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