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过去十年中国大陆眼部损伤医学治疗的发展。

Development of medical treatment for eye injuries in the mainland of China over the past decade.

作者信息

Wang Chang-Guan, Ma Zhi-Zhong

机构信息

Peking University Eye Center, The Third Hospital of Peking University, Beijing 100083, China.

出版信息

Chin J Traumatol. 2016 Dec 1;19(6):311-316. doi: 10.1016/j.cjtee.2016.09.002.

DOI:10.1016/j.cjtee.2016.09.002
PMID:28088931
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5198919/
Abstract

In the article, the development of medical treatment for eye injuries in the mainland of China was reviewed. According to the data provided in Eye Injury Vitrectomy Study (EIVS), 27% of 72 eyes with no light perception (NLP) gained recovery in term of antomy and visual function. Vitrectomy initiated at more than 4 weeks after open eye injury is an independent risk factor for developing PVR. Prognosis of anatomy and visual function of the injured eye with PVR is markedly worse than that without PVR. Serious injuries of ciliary body, choroid and retina are three key parts of the eye with NLP. The concept that the treatment of the eye injury gradually focus on the whole globe is embodied. The data from 13575 in patients with traumatic eyes in 14 hospitals revealed that the rate of immediate enucleation was remarkable reduced with comparison of 20 years ago.

摘要

本文回顾了中国大陆眼外伤的医学治疗进展。根据眼外伤玻璃体切除术研究(EIVS)提供的数据,72只无光感(NLP)眼中有27%在解剖结构和视觉功能方面获得了恢复。开放性眼外伤后4周以上开始的玻璃体切除术是发生增殖性玻璃体视网膜病变(PVR)的独立危险因素。伴有PVR的伤眼的解剖结构和视觉功能预后明显差于不伴有PVR的伤眼。睫状体、脉络膜和视网膜的严重损伤是无光感眼的三个关键部位。这体现了眼外伤治疗逐渐着眼于眼球整体的理念。来自14家医院13575例眼外伤患者的数据显示,与20年前相比,一期眼球摘除率显著降低。

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Epidemiology of Ocular Trauma in the Elderly: A Population-Based Study.老年人眼外伤的流行病学:一项基于人群的研究。
J Curr Ophthalmol. 2023 Aug 11;35(1):79-85. doi: 10.4103/joco.joco_53_23. eCollection 2023 Jan-Mar.
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Damage to the eye and optic nerve in seriously traumatized patients with concomitant head injury: analysis of 84,627 cases from the TraumaRegister DGU® between 2002 and 2015.严重创伤合并头部损伤患者的眼部和视神经损伤:2002 年至 2015 年创伤登记处 DGU® 中 84627 例患者的分析。
Scand J Trauma Resusc Emerg Med. 2020 Mar 2;28(1):15. doi: 10.1186/s13049-020-0712-5.
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Optimal timing of vitrectomy for severe mechanical ocular trauma: A retrospective observational study.严重机械性眼外伤玻璃体切除术的最佳时机:一项回顾性观察研究。
Sci Rep. 2019 Nov 29;9(1):18016. doi: 10.1038/s41598-019-54472-9.

本文引用的文献

1
Caspase-3 inhibitor Z-DEVD-FMK enhances retinal ganglion cell survival and vision restoration after rabbit traumatic optic nerve injury.半胱天冬酶-3抑制剂Z-DEVD-FMK可提高兔外伤性视神经损伤后视网膜神经节细胞的存活率并促进视力恢复。
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Retina. 2015 Jan;35(1):105-10. doi: 10.1097/IAE.0000000000000261.
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Increased Th17 cells and IL‑17 in rats with traumatic optic neuropathy.外伤性视神经病变大鼠中Th17细胞和白细胞介素-17增加。
Mol Med Rep. 2014 Oct;10(4):1954-8. doi: 10.3892/mmr.2014.2448. Epub 2014 Aug 5.
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Causative organisms of post-traumatic endophthalmitis: a 20-year retrospective study.创伤后眼内炎的病原体:一项 20 年回顾性研究。
BMC Ophthalmol. 2014 Mar 25;14:34. doi: 10.1186/1471-2415-14-34.
6
Treatment for suprachoroidal silicone oil migration following surgeries for open globe injuries.治疗开放性眼球损伤手术后脉络膜上腔硅油迁移。
Can J Ophthalmol. 2013 Aug;48(4):307-11. doi: 10.1016/j.jcjo.2013.03.005.
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Enucleation versus evisceration in ocular trauma: a retrospective review and study of current literature.眼外伤中眼球摘除术与眼内容剜出术的比较:一项回顾性综述及当前文献研究
Orbit. 2013 Dec;32(6):356-61. doi: 10.3109/01676830.2013.764452. Epub 2013 Aug 2.
8
Open globe eye injury characteristics and prognostic factors in southern Israel: a retrospective epidemiologic review of 10 years experience.以色列南部开放性眼球损伤的特征及预后因素:一项基于10年经验的回顾性流行病学研究
Isr Med Assoc J. 2013 Mar;15(3):158-62.
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