Kim Ji Wan, Ryu Jin-Sook, Baek Sora, Byun Seong-Eun, Chang Jae Suk
Department of Orthopedic Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.
Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
J Orthop Sci. 2017 May;22(3):457-462. doi: 10.1016/j.jos.2016.12.014. Epub 2017 Jan 6.
Bone SPECT can be used after a femur neck fracture to assess the circulation of the femoral head in the immediate postoperative period because the blood supply is one of the major factors affecting bone uptake of radiotracer on bone scintigraphy. The purpose of our present study was to investigate whether osteonecrosis of the femoral head (OFH) after internal fixation of femoral neck fracture could be predicted by early and late bone SPECT.
This retrospective cohort study enrolled 44 patients (33 women; mean age, 66.9 years) who underwent surgical fixation for femoral neck fractures. Early and late bone SPECT images were obtained within 2 weeks postoperatively and at 3 months postoperatively. Patients were followed up for a minimum of 24 months (average, 34 months).
OFH developed in 9 out of 44 patients but no patient showed nonunion. Seventeen patients with normal femoral head uptake on early bone SPECT were healed. Of 27 patients with decreased femoral head uptake on early bone SPECT, 2 patients developed OFH on radiography before 3 months postoperatively, 18 patients recovered to normal uptake on the late SPECT, and the remaining 7 patients still showed decreased uptake on the late SPECT at 3 months postoperatively. All of these 7 cases finally developed OFH on radiography.
Bone SPECT can reliably predict the possibility of OFH with after femoral neck fracture at least 3 months after surgery, while early bone SPECT showed low specificity.
Clinical.
股骨颈骨折后可进行骨SPECT检查,以评估术后即刻股骨头的血运情况,因为血供是影响骨闪烁显像中放射性示踪剂骨摄取的主要因素之一。本研究的目的是探讨早期和晚期骨SPECT能否预测股骨颈骨折内固定术后股骨头缺血性坏死(OFH)。
本回顾性队列研究纳入了44例行股骨颈骨折手术固定的患者(33例女性;平均年龄66.9岁)。分别在术后2周内及术后3个月获得早期和晚期骨SPECT图像。对患者进行至少24个月(平均34个月)的随访。
44例患者中有9例发生OFH,但无患者出现骨不连。早期骨SPECT显示股骨头摄取正常的17例患者愈合。早期骨SPECT显示股骨头摄取降低的27例患者中,2例在术后3个月内X线片上出现OFH,18例晚期SPECT恢复至正常摄取,其余7例术后3个月晚期SPECT仍显示摄取降低。这7例最终均在X线片上出现OFH。
骨SPECT能够可靠地预测股骨颈骨折术后至少3个月发生OFH的可能性,而早期骨SPECT的特异性较低。
临床研究。