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手术治疗加特纳管囊肿的临床表现及预后

Clinical Manifestations and Outcomes in Surgically Managed Gartner Duct Cysts.

作者信息

Cope Adela G, Laughlin-Tommaso Shannon K, Famuyide Abimbola O, Gebhart John B, Hopkins Matthew R, Breitkopf Daniel M

机构信息

Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota.

Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota.

出版信息

J Minim Invasive Gynecol. 2017 Mar-Apr;24(3):473-477. doi: 10.1016/j.jmig.2017.01.003. Epub 2017 Jan 12.

DOI:10.1016/j.jmig.2017.01.003
PMID:28089812
Abstract

STUDY OBJECTIVE

Gartner duct cysts (GDCs) are rare embryological remnants of the mesonephric duct with the majority of cases discovered incidentally in asymptomatic patients. The largest prior published series evaluating the surgical management of GDCs included 4 patients. The present study aimed to determine the manifestations and outcomes of surgically managed patients with GDCs with important implications for surveillance, monitoring, and management.

DESIGN

A retrospective chart review (Canadian Task Force classification III).

SETTING

A tertiary care center.

PATIENTS

All women diagnosed with GDCs from January 1994 to April 2014 at our institution were identified. Patients were included if they underwent surgical management and had GDCs confirmed by pathology. One hundred twenty-four charts were manually reviewed, and 29 patients were included in the analysis.

INTERVENTIONS

All patients underwent surgical management, which included vaginal excision or marsupialization.

MEASUREMENTS AND MAIN RESULTS

A total of 29 patients met the inclusion criteria for this study. The median age of the patients included in the analysis was 36 years old. Eleven patients were asymptomatic at the time of diagnosis (37.9%). The reason for surgical intervention was not available in 9 of these patients. Surgical intervention was performed in 2 of the 11 asymptomatic patients because of an increasing size of the lesion during observation. Presenting symptoms included dyspareunia or pain with tampon placement (37.9%), pelvic pain or pressure (24.1%), pelvic mass or bulge (17.2%), and urinary incontinence (6.9%). Preoperative imaging studies were obtained in 62% of patients; ultrasound was used in 44.4%, computed tomographic scanning in 22.2%, magnetic resonance imaging in 16.7%, and multiple modalities in 16.7%. Approximately 10% were found to have other genitourinary anomalies, including a bladder cyst, urethral diverticulum, and a solitary right kidney with uterine didelphis and septate vagina. The average cyst size was 3.5 cm (±1.8 cm). Surgical excision of GDCs was performed in all except for 3 cases of marsupialization. No intraoperative complications occurred. The median follow-up was 82 months (range, 0-246 months). One patient had possible recurrence with dyspareunia and protruding tissue diagnosed 14 months postoperatively. There were no other postoperative complications in the follow-up period.

CONCLUSION

GDCs are rare pelvic masses that are often asymptomatic but may present with dyspareunia, pelvic pain or pressure, pelvic mass or bulge, or urinary symptoms. Excision or marsupialization is successful in the majority of cases without significant morbidity.

摘要

研究目的

加特纳管囊肿(GDCs)是中肾管罕见的胚胎学残余物,大多数病例在无症状患者中偶然发现。此前发表的评估GDCs手术治疗的最大系列研究纳入了4例患者。本研究旨在确定接受手术治疗的GDCs患者的表现和结局,这对监测、监控和管理具有重要意义。

设计

一项回顾性病历审查(加拿大工作组分类III级)。

地点

一家三级医疗中心。

患者

确定了1994年1月至2014年4月在我们机构被诊断为GDCs的所有女性。如果患者接受了手术治疗且病理证实为GDCs,则纳入研究。人工审查了124份病历,29例患者纳入分析。

干预措施

所有患者均接受手术治疗,包括经阴道切除或袋形缝合术。

测量指标和主要结果

共有29例患者符合本研究的纳入标准。分析中纳入患者的中位年龄为36岁。11例患者在诊断时无症状(37.9%)。其中9例患者未记录手术干预的原因。11例无症状患者中有2例因观察期间病变增大而接受了手术干预。主要症状包括性交困难或放置卫生棉条时疼痛(37.9%)、盆腔疼痛或压迫感(24.1%)、盆腔肿块或隆起(17.2%)以及尿失禁(6.9%)。62%的患者进行了术前影像学检查;44.4%使用了超声,22.2%使用了计算机断层扫描,16.7%使用了磁共振成像,16.7%使用了多种检查方法。约10%的患者被发现有其他泌尿生殖系统异常,包括膀胱囊肿、尿道憩室以及伴有双子宫和纵隔阴道的孤立右肾。囊肿平均大小为3.5 cm(±1.8 cm)。除3例行袋形缝合术外,所有患者均接受了GDCs手术切除。未发生术中并发症。中位随访时间为82个月(范围0 - 246个月)。1例患者术后14个月出现性交困难和组织突出,可能为复发。随访期间无其他术后并发症。

结论

GDCs是罕见的盆腔肿块,通常无症状,但可能表现为性交困难、盆腔疼痛或压迫感、盆腔肿块或隆起或泌尿系统症状。大多数情况下,切除或袋形缝合术成功,且发病率不高。

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