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加特纳管囊肿:手术治疗综述及使用荧光素染料的新技术

Gartner's duct cysts: a review of surgical management and a new technique using fluorescein dye.

作者信息

Niu Sida, Didde Ryan D, Schuchmann Jennifer K, Zoorob Dani

机构信息

Department of Urology, University of Kansas Medical Center, Kansas City, KS, USA.

University of Kansas School of Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd. MS 3016, Kansas City, KS, 66160, USA.

出版信息

Int Urogynecol J. 2020 Jan;31(1):55-61. doi: 10.1007/s00192-019-04091-9. Epub 2019 Aug 30.

DOI:10.1007/s00192-019-04091-9
PMID:31471622
Abstract

INTRODUCTION AND HYPOTHESIS

Gartner's duct cysts (GDC) are benign lesions that may become symptomatic, leading to surgical intervention. There is no standard surgical technique for management of GDC. This article provides a comprehensive review of surgical the management of GDC. We also present a new technique using fluorescein dye to help delineate GDC walls and facilitate complete cyst excision.

METHODS

We conducted a PubMed search for English-language articles without a defined time range. The search combined subject headings, title, abstract, and text words relating to Gartner duct cysts. Articles describing surgical management of GDC were included. Exclusion criteria included inadequate diagnosis of GDC, infected cysts, nonsurgical management, or article unavailable for interlibrary loan. A novel approach using intra-cyst fluorescein dye injection is described.

RESULTS

Two hundred sixty-seven articles were identified via PubMed, and 34 articles were included in the review based on eligibility criteria. Concomitant genitourinary malformations occurred in 19 of the 92 surgically managed patients. Surgical techniques included cyst excision (50 patients), tetracycline injection following aspiration (15), marsupialization (14), unroofing/partial excision (9), and puncture/evacuation (4). Recurrences occurred in 4, 1, 0, 0, and 1 patient, respectively. One patient underwent uncomplicated fluorescein dye-assisted cyst excision with no recurrence 30 months post-procedure.

CONCLUSIONS

The low incidence of GDCs necessitating surgical intervention has resulted in a lack of standard surgical technique, especially in patients with concurrent genitourinary malformations. Utilizing fluorescein dye provides a surgical method that can help confirm the absence of urologic involvement as well as facilitate precise excision of GDC.

摘要

引言与假设

加特纳管囊肿(GDC)是良性病变,可能出现症状,从而需要手术干预。目前尚无用于治疗GDC的标准手术技术。本文对GDC的手术治疗进行了全面综述。我们还介绍了一种使用荧光素染料的新技术,以帮助勾勒GDC壁并促进囊肿完整切除。

方法

我们在PubMed上搜索了无特定时间范围限制的英文文章。搜索结合了与加特纳管囊肿相关的主题词、标题、摘要和文本词汇。纳入描述GDC手术治疗的文章。排除标准包括GDC诊断不充分、囊肿感染、非手术治疗或无法通过馆际互借获取的文章。描述了一种使用囊内注射荧光素染料的新方法。

结果

通过PubMed检索到267篇文章,根据纳入标准,34篇文章被纳入综述。92例接受手术治疗的患者中有19例伴有泌尿生殖系统畸形。手术技术包括囊肿切除(50例患者)、抽吸后注射四环素(15例)、袋形缝合术(14例)、去顶/部分切除(9例)和穿刺/抽液(4例)。复发分别发生在4例、1例、0例、0例和1例患者中。1例患者接受了无并发症的荧光素染料辅助囊肿切除,术后30个月无复发。

结论

需要手术干预的GDC发病率较低,导致缺乏标准手术技术,尤其是在伴有泌尿生殖系统畸形的患者中。使用荧光素染料提供了一种手术方法,有助于确认无泌尿系统受累,并便于精确切除GDC。

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本文引用的文献

1
A Gartner Duct Cyst Masquerading as Anterior Vaginal Prolapse.一例伪装成阴道前壁脱垂的加特纳管囊肿
Obstet Gynecol. 2017 Nov;130(5):1039-1041. doi: 10.1097/AOG.0000000000002315.
2
Neonatal Gartner Duct Cyst: Two Case Reports and Literature Review.新生儿加特纳管囊肿:两例报告及文献综述
Dev Period Med. 2017;21(1):35-37. doi: 10.34763/devperiodmed.20172101.3537.
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Gartner's Duct Cyst.加特纳管囊肿
调查区块链技术对银行住房信贷风险控制策略对家庭消费计划的影响。
Comput Intell Neurosci. 2022 Jul 31;2022:7021384. doi: 10.1155/2022/7021384. eCollection 2022.
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Large Gartner cyst of the posterior vaginal fornix.阴道后穹窿巨大加特纳囊肿。
BMJ Case Rep. 2022 Jul 11;15(7):e249458. doi: 10.1136/bcr-2022-249458.
N Engl J Med. 2017 Apr 6;376(14):e27. doi: 10.1056/NEJMicm1609983.
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Clinical Manifestations and Outcomes in Surgically Managed Gartner Duct Cysts.手术治疗加特纳管囊肿的临床表现及预后
J Minim Invasive Gynecol. 2017 Mar-Apr;24(3):473-477. doi: 10.1016/j.jmig.2017.01.003. Epub 2017 Jan 12.
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Perivaginal benign masses: diagnosis and therapy in a series of 66 women.阴道周围良性肿块:66例女性患者的诊断与治疗
Arch Gynecol Obstet. 2017 Feb;295(2):367-374. doi: 10.1007/s00404-016-4234-3. Epub 2016 Nov 12.
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Posterior vaginal wall Gartner's duct cyst.阴道后壁加特纳管囊肿。
J Midlife Health. 2015 Oct-Dec;6(4):187-90. doi: 10.4103/0976-7800.172354.
7
Giant Gartner duct cyst and elevated CA-125.巨大加特纳管囊肿与CA-125升高
J Pediatr Adolesc Gynecol. 2014 Dec;27(6):e137-8. doi: 10.1016/j.jpag.2013.12.007. Epub 2014 Jun 18.
8
A vaginal Gartner duct cyst presenting as a cystocele during pregnancy.孕期表现为膀胱膨出的阴道加德纳管囊肿。
Eur J Obstet Gynecol Reprod Biol. 2014 Sep;180:202-4. doi: 10.1016/j.ejogrb.2014.05.015. Epub 2014 Jun 2.
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Vaginal Gartner cysts: clinical report of four cases and a bibliographic review.阴道加特纳囊肿:4例临床报告及文献复习
Arch Esp Urol. 2014 Mar;67(2):181-4.
10
Large mesonephric cyst with acute adnexal torsion in a teenage girl.一名青少年女性患有巨大中肾囊肿并伴有急性附件扭转。
J Pediatr Adolesc Gynecol. 2012 Dec;25(6):e143-5. doi: 10.1016/j.jpag.2012.06.009. Epub 2012 Oct 23.