Poggioli Michela, Minichilli Fabrizio, Bononi Tiziana, Meghi Pasquina, Andre Paolo, Crecchi Alessandra, Rossi Bruno, Carboncini Maria Chiara, Ottolini Alberto, Bonfiglio Luca
Unità Operativa Neuropsichiatria Infanzia e Adolescenza (UONPIA), ASST Fatebenefratelli e Sacco, 20157 Milano, Italy.
Unit of Environmental Epidemiology, Institute of Clinical Physiology, National Council of Research, 56124 Pisa, Italy.
Neural Plast. 2016;2016:4323792. doi: 10.1155/2016/4323792. Epub 2016 Dec 20.
Preterm children have an increased risk of neurodevelopmental impairments which include psychomotor and language retardation. The objectives of the present retrospective cohort study were to examine the effects of an individually adapted, home-based, and family-centred early developmental habilitation program on neurodevelopmental and behavioural outcomes of very preterm children compared with a standard follow-up at 2 years' corrected age. Enrolled infants were retrospectively assigned to the intervention group (61 subjects) or to the control group (62 subjects) depending on whether they had or had not carried out a home-based family-centred early developmental habilitation program focused on environmental enrichment, parent-guided environmental interaction, and infant development. Developmental outcome was assessed for both groups at 24 months' corrected age using the Bayley Scales of Infant Development 2nd Edition. Intervention significantly improved both cognitive and behavioural outcomes. In addition, males had significantly lower scores than females either before or after treatment. However, the treatment was effective in both genders to the same extent. In conclusion, a timely updated environment suitable to the infant's developmental needs could provide the best substrate where the parent-infant relationship can be practised with the ultimate goal of achieving further developmental steps.
早产儿出现神经发育障碍的风险增加,这些障碍包括精神运动和语言发育迟缓。本回顾性队列研究的目的是,与2岁矫正年龄时的标准随访相比,研究一项个体化、基于家庭且以家庭为中心的早期发育康复计划对极早产儿神经发育和行为结果的影响。根据婴儿是否实施了一项以家庭为中心、注重环境丰富化、家长指导的环境互动和婴儿发育的早期发育康复计划,将纳入的婴儿回顾性地分为干预组(61名受试者)或对照组(62名受试者)。在24个月矫正年龄时,使用贝利婴儿发展量表第二版对两组的发育结果进行评估。干预显著改善了认知和行为结果。此外,无论治疗前后,男性的得分均显著低于女性。然而,治疗对两性的效果程度相同。总之,一个及时更新的、适合婴儿发育需求的环境可以提供最佳基础,在此基础上可以实践亲子关系,最终目标是实现进一步的发育阶段。