Evaluation of the resistance of Enterobacteriaceae strains to antibiotics--comparison of strains from clinical material versus environment.

The authors analyzed resistance to antibiotics of bacterial strains from the family of enterobacteriaceae comparing the resistance of two sets of strains, one set being strains isolated from clinical material of patients, the other being those isolated from municipal waste water of the 4th district of Bratislava. Referring to higher index of resistance in strains isolated from outer environment, they draw attention to high number of strains resistant to ampicillin and tetracyclin in clinical material and that of gentamicin-resistant ones from outer environment. Some views on standardization of empirical antibiotic therapy of infections due to strains from clinical material and outer environment are formulated and changes in the antibiotic spectrum effectivity as compared with past results as well as possible unsatisfactory success in treatment by means of currently applied broad spectrum antibiotics in cases of empiric therapy of infections are pointed to. Information on incidence of polyresistant strains of Enterobacteriaceae in outer environment and municipal waste water is presented.