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钩端螺旋体病的多样表现:来自印度北部一家三级护理医院的经验

Varied presentations of leptospirosis: experience from a tertiary care hospital in north India.

作者信息

Chaudhry Rama, Saigal Karnika, Bahadur Tej, Kant Kamla, Chourasia Bishwanath, Gupta Nitin

机构信息

1 Professor, Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.

2 Ex Senior Resident, Department of Microbiology All India Institute of Medical Sciences, New Delhi, India.

出版信息

Trop Doct. 2017 Apr;47(2):128-132. doi: 10.1177/0049475516687431. Epub 2017 Jan 16.

Abstract

Leptospirosis has been recognised as an emerging global public health problem. The aim of our study was to explore the epidemiological and clinical pattern of disease occurrence in suspected cases and to search for any existing co-infections. Ours was a retrospective study in patients with acute febrile illness in north India over a period of three years (April 2011 to June 2014). Serological diagnosis of leptospirosis was made using the PanBio IgM ELISA kit. Using modified Faine's criteria, presumptive and possible diagnosis was made in 57% and 34% cases, respectively. Most of the affected population was resident in north and central India. Nineteen patients showed co-infection with other common pathogens prevailing locally. There is a need to increase awareness and understand the local sero-epidemiological pattern of leptospirosis so that timely preventive and curative action may be taken by healthcare authorities.

摘要

钩端螺旋体病已被公认为一个新出现的全球公共卫生问题。我们研究的目的是探讨疑似病例中疾病发生的流行病学和临床模式,并寻找任何现有的合并感染情况。我们对印度北部三年(2011年4月至2014年6月)期间患有急性发热性疾病的患者进行了一项回顾性研究。使用PanBio IgM ELISA试剂盒进行钩端螺旋体病的血清学诊断。根据改良的费恩标准,分别在57%和34%的病例中做出了推定诊断和可能诊断。大多数受影响人群居住在印度北部和中部。19名患者显示与当地流行的其他常见病原体合并感染。有必要提高认识并了解钩端螺旋体病的当地血清流行病学模式,以便卫生保健当局能够及时采取预防和治疗行动。

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