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"Cross-sectional" stepped wedge designs always reduce the required sample size when there is no time effect.

作者信息

Zhou Xin, Liao Xiaomei, Spiegelman Donna

机构信息

Departments of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, 677 Hungtington Avenue, Boston, MA 02115, USA.

AbbVie Inc., Data and Statistical Sciences, 1 North Waukegan Road, North Chicago, IL 60064, USA.

出版信息

J Clin Epidemiol. 2017 Mar;83:108-109. doi: 10.1016/j.jclinepi.2016.12.011. Epub 2017 Jan 16.

DOI:10.1016/j.jclinepi.2016.12.011
PMID:28093263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5517056/
Abstract
摘要

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Systematic review showed that stepped-wedge cluster randomized trials often did not reach their planned sample size.系统评价显示,阶梯式楔形簇随机试验往往无法达到其计划的样本量。
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本文引用的文献

1
Impact of early initiation versus national standard of care of antiretroviral therapy in Swaziland's public sector health system: study protocol for a stepped-wedge randomized trial.斯威士兰公共部门卫生系统中抗逆转录病毒疗法早期启动与国家标准治疗的影响:一项阶梯楔形随机试验的研究方案
Trials. 2017 Aug 18;18(1):383. doi: 10.1186/s13063-017-2128-8.
2
Institutionalizing postpartum intrauterine device (IUD) services in Sri Lanka, Tanzania, and Nepal: study protocol for a cluster-randomized stepped-wedge trial.在斯里兰卡、坦桑尼亚和尼泊尔将产后宫内节育器(IUD)服务制度化:一项整群随机阶梯式楔形试验的研究方案
BMC Pregnancy Childbirth. 2016 Nov 21;16(1):362. doi: 10.1186/s12884-016-1160-0.
3
A note on "Design and analysis of stepped wedge cluster randomized trials".关于《阶梯楔形整群随机试验的设计与分析》的一则注释
Contemp Clin Trials. 2015 Nov;45(Pt B):338-339. doi: 10.1016/j.cct.2015.09.011. Epub 2015 Sep 21.
4
The efficiency of stepped wedge vs. cluster randomized trials: stepped wedge studies do not always require a smaller sample size.阶梯楔形试验与整群随机试验的效率:阶梯楔形研究并不总是需要更小的样本量。
J Clin Epidemiol. 2013 Dec;66(12):1427-8. doi: 10.1016/j.jclinepi.2013.07.007. Epub 2013 Sep 10.
5
The stepped wedge cluster randomized trial always requires fewer clusters but not always fewer measurements, that is, participants than a parallel cluster randomized trial in a cross-sectional design. In reply.阶梯楔形整群随机试验通常需要的群组较少,但在横断面设计中,其测量次数(即参与者数量)并不总是比平行整群随机试验少。作为回应。
J Clin Epidemiol. 2013 Dec;66(12):1428. doi: 10.1016/j.jclinepi.2013.07.008. Epub 2013 Sep 8.
6
Stepped wedge designs could reduce the required sample size in cluster randomized trials.阶梯式楔形设计可以减少群组随机试验所需的样本量。
J Clin Epidemiol. 2013 Jul;66(7):752-8. doi: 10.1016/j.jclinepi.2013.01.009. Epub 2013 Mar 22.
7
Design and analysis of stepped wedge cluster randomized trials.阶梯楔形整群随机试验的设计与分析
Contemp Clin Trials. 2007 Feb;28(2):182-91. doi: 10.1016/j.cct.2006.05.007. Epub 2006 Jul 7.