Feltgen N, Pielen A
Augenklinik der Universitätsmedizin Göttingen (UMG), Robert-Koch-Str. 40, 37075, Göttingen, Deutschland.
Augenklinik, Medizinische Hochschule Hannover (MHH), Hannover, Deutschland.
Ophthalmologe. 2017 Feb;114(2):177-190. doi: 10.1007/s00347-016-0432-4.
Retinal artery occlusion leads to profound visual impairment in the affected eye. It is rarely caused by local ophthalmic pathologies. Most patients present with a large number of cardio- and cerebrovascular risk factors. Visual loss is the leading symptom in central retinal artery occlusion (CRAO), whereas a circumscribed visual field defect is claimed in branch retinal artery occlusion (BRAO). Although many attempts have been made to improve the course of the disease, no effective therapy is available. There is some hope that intravenous fibrinolysis could influence the natural course but the therapeutic window is small (ca. 4.5 h), and treatment efficacy is still not proven. It is important for ophthalmologists to guide the patients to a comprehensive and prompt neurological and cardiological diagnostic work-up.
视网膜动脉阻塞会导致患眼严重视力受损。它很少由局部眼科疾病引起。大多数患者存在大量心脑血管危险因素。视力丧失是视网膜中央动脉阻塞（CRAO）的主要症状，而视网膜分支动脉阻塞（BRAO）则表现为局限性视野缺损。尽管人们已多次尝试改善该病的病程，但尚无有效的治疗方法。静脉溶栓有可能影响疾病的自然病程，但治疗窗较小（约4.5小时），且治疗效果仍未得到证实。眼科医生引导患者进行全面、及时的神经科和心脏科诊断检查非常重要。
