De Salvo Gabriella, Oshallah Mohamed, Sepetis Anastasios E, Borbara Ramez, Oliverio Giovanni William, Meduri Alessandro, Frisina Rino, Jacob Aby
Ophthalmology Department, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Biomedical, Dental and Morphological and Functional Images Sciences Department, University of Messina, 98122 Messina, Italy.
Diagnostics (Basel). 2023 Nov 10;13(22):3428. doi: 10.3390/diagnostics13223428.
to assess the tomographic retinal layers' thickness in eyes affected by branch retinal artery occlusion (BRAO) and to compare it to those of patients affected by primary open angle glaucoma (POAG). retrospective review of 27 patients; 16 with BRAO (16 eyes) and 11 with POAG (20 eyes) were identified among those who received SD-OCT scans, including analysis of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), neuroretinal rim (NRR), circumpapillary RNFL at 3.5 mm and hemisphere asymmetry (HA). the total IPL and INL thinning difference between the two groups was statistically significant ( = 0.0067 and < 0.0001, respectively). The HA difference for the total macular thinning, mRNFL, GCL, IPL and INL ( < 0.0001) was also statistically significant. The analysis of the average total retinal thinning, total mRNFL and GCL thinning showed no statistically significant difference between the two groups. unilateral inner retinal thinning may represent a sign of temporal BRAO, particularly for INL thinning and HA difference over 17µm in total retinal layer thinning. This information is particularly useful in the diagnosis of previous, undiagnosed BRAO and may help prevent further retinal arterial occlusion and possible cerebrovascular incidents.
评估视网膜分支动脉阻塞（BRAO）患者眼部断层视网膜各层的厚度，并将其与原发性开角型青光眼（POAG）患者的厚度进行比较。对27例患者进行回顾性研究；在接受频域光学相干断层扫描（SD - OCT）的患者中，确定了16例BRAO患者（16只眼）和11例POAG患者（20只眼），包括对黄斑视网膜神经纤维层（mRNFL）、神经节细胞层（GCL）、内网状层（IPL）、内核层（INL）、神经视网膜边缘（NRR）、3.5 mm处视乳头周围视网膜神经纤维层（circumpapillary RNFL）和半球不对称性（HA）的分析。两组之间IPL和INL总变薄差异具有统计学意义（分别为 = 0.0067和 < 0.0001）。黄斑总变薄、mRNFL、GCL、IPL和INL的HA差异（< 0.0001）也具有统计学意义。两组之间平均总视网膜变薄、总mRNFL和GCL变薄的分析无统计学意义。单侧视网膜内层变薄可能是颞侧BRAO的一个征象，特别是对于INL变薄和总视网膜层变薄超过17µm的HA差异。该信息在诊断既往未诊断的BRAO中特别有用，可能有助于预防进一步的视网膜动脉阻塞和可能的脑血管事件。
