Gomes-Fonseca João, Vilaça João L, Henriques-Coelho Tiago, Direito-Santos Bruno, Pinho António C M, Fonseca Jaime C, Correia-Pinto Jorge
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; ICVS/3B's-PT, Government Associate Laboratory, Braga/Guimarães, Portugal.
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; ICVS/3B's-PT, Government Associate Laboratory, Braga/Guimarães, Portugal; DIGARC-Technology School, Polytechnic Institute of Cávado and Ave, Barcelos, Portugal.
J Pediatr Surg. 2017 Jul;52(7):1089-1097. doi: 10.1016/j.jpedsurg.2016.12.029. Epub 2017 Jan 7.
The objective is to present a new methodology to assess quantitatively the impact of bar removal on the anterior chest wall, among patients with pectus excavatum who have undergone the Nuss procedure, and present a preliminary study using this methodology.
We propose to acquire, for each patient, the surface of the anterior chest wall using a three-dimensional laser scanner at subsequent time points (short term: before and after surgery; long term: follow-up visit, 6months, and 12months after surgery). After surfaces postprocessing, the changes are assessed by overlapping and measuring the distances between surfaces. In this preliminary study, three time points were acquired and two assessments were performed: before vs after bar removal (early) and before vs 2-8weeks after bar removal (interim). In 21 patients, the signed distances and volumes between surfaces were computed and the data analysis was performed.
This methodology revealed useful for monitoring changes in the anterior chest wall. On average, the mean, maximum, and volume variations, in the early assessment, were -0.1±0.1cm, -0.6±0.2cm, and 47.8±22.2cm, respectively; and, in the interim assessment, were -0.5±0.2cm, -1.3±0.4cm, and 122.1±47.3cm, respectively (p<0.05). Data analysis revealed that the time the bar was in situ was inversely and significantly correlated with postretraction and was a relevant predictor of its decrease following surgery (p<0.05). Additionally, gender and age suggested influencing the outcome.
This methodology is novel, objective and safe, helping on follow-up of pectus excavatum patients. Moreover, the preliminary study suggests that the time the bar was in situ may be the main determinant of the anterior chest wall retraction following bar removal. Further studies should continue to corroborate and reinforce the preliminary findings, by increasing the sample size and performing long-term assessments.
III.
本研究旨在提出一种新方法,用于定量评估鸡胸患者接受努氏手术(Nuss手术)后取出钢板对前胸壁的影响,并展示使用该方法的初步研究结果。
我们建议在后续时间点(短期:手术前后;长期:术后6个月和12个月的随访),使用三维激光扫描仪获取每位患者的前胸壁表面。在对表面进行后处理后,通过重叠和测量表面之间的距离来评估变化。在这项初步研究中,获取了三个时间点的数据,并进行了两次评估:取出钢板前与取出后(早期)以及取出钢板前与取出后2 - 8周(中期)。对21例患者计算了表面之间的有符号距离和体积,并进行了数据分析。
该方法显示出对监测前胸壁变化有用。在早期评估中,平均、最大和体积变化分别为 -0.1±0.1cm、-0.6±0.2cm和47.8±22.2cm;在中期评估中,分别为 -0.5±0.2cm、-1.3±0.4cm和122.1±47.3cm(p<0.05)。数据分析显示,钢板在位时间与回缩呈显著负相关,是术后回缩减少的一个相关预测因素(p<0.05)。此外,性别和年龄似乎对结果有影响。
该方法新颖、客观且安全,有助于鸡胸患者的随访。此外,初步研究表明,钢板在位时间可能是取出钢板后前胸壁回缩的主要决定因素。进一步的研究应通过增加样本量和进行长期评估来继续证实和强化这些初步发现。
III级