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漏斗胸 Nuss 修复术后延迟取出胸骨固定矫正器对治疗效果的影响:一项回顾性分析。

Impact of delayed removal of pectus bar on outcomes following Nuss repair: a retrospective analysis.

机构信息

Division of Thoracic Surgery, Department of Surgery, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.

School of Medicine, Tzu Chi University, Hualien, Taiwan.

出版信息

J Cardiothorac Surg. 2024 Mar 28;19(1):160. doi: 10.1186/s13019-024-02685-z.

Abstract

BACKGROUND

Usually, pectus bars are removed 3 years after the Nuss procedure in patients with pectus excavatum. However, the optimal timing for postoperative pectus bar removal remains undefined. Our study investigated the effects of delayed pectus bar removal after Nuss repairs.

METHODS

Retrospective data were collected on patients who underwent Nuss procedures for pectus excavatum and had their bars removed from August 2014 to December 2020. Patients with correction periods > 3 years were divided into group A (< 6 years) and group B (≥ 6 years). Propensity score matching was used to compare complications and radiological outcomes associated with bar removal.

RESULTS

Of the 542 patients who underwent bar removal, 451 (Group A: 419 patients, Group B: 32) had correction duration > 3 years. The average correction duration was 4.5 ± 1.4 years. After propensity score matching analysis, group B [median duration: 8.0 (6.0-16.2) years] exhibited significantly longer median operative times (85 vs. 55 min; P = 0.026), higher callus formation rates (68.8% vs. 46.9%; P = 0.029), and greater median intraoperative blood loss (35 vs. 10 mL; P = 0.017) than group A [median duration: 4.2 (3.0-5.9) years]. However, following bar removal, the groups showed no statistical differences in the surgical complication rates (group A: 6.3% vs. group B: 9.4%; P = 0.648) or median ratio of radiological improvement (an improvement on the Haller index on chest radiography; 21.0% vs. 22.2%; P = 0.308).

CONCLUSIONS

Delaying pectus bar removal after Nuss repair presents certain challenges but does not compromise overall outcomes. These findings suggest that a longer correction period may be unnecessary. However, further multicenter studies with long-term follow-up are warranted to assess long-term outcomes.

摘要

背景

通常情况下,漏斗胸患者在接受 Nuss 手术后 3 年内会取出矫正器,但术后何时取出矫正器仍未确定。本研究旨在探讨 Nuss 修复术后延迟取出矫正器的效果。

方法

回顾性收集 2014 年 8 月至 2020 年 12 月接受 Nuss 手术治疗漏斗胸且矫正器取出的患者资料。将矫正持续时间>3 年的患者分为 A 组(<6 年)和 B 组(≥6 年)。采用倾向评分匹配法比较两组患者矫正器取出相关并发症及影像学结果。

结果

542 例行矫正器取出术的患者中,451 例(A 组:419 例,B 组:32 例)的矫正持续时间>3 年。平均矫正持续时间为 4.5±1.4 年。经倾向评分匹配分析后,B 组(中位数:8.0 [6.0-16.2]年)的手术时间(85 分钟比 55 分钟;P=0.026)、骨痂形成率(68.8%比 46.9%;P=0.029)和术中出血量(35 毫升比 10 毫升;P=0.017)均显著高于 A 组(中位数:4.2 [3.0-5.9]年)。但矫正器取出后,两组的手术并发症发生率(A 组:6.3%比 B 组:9.4%;P=0.648)或影像学改善程度中位数(胸廓 X 射线检查的 Haller 指数改善率;21.0%比 22.2%;P=0.308)均无统计学差异。

结论

Nuss 修复术后延迟取出矫正器存在一定挑战,但不影响总体疗效。这提示较长的矫正期可能并非必需。然而,需要进一步开展多中心、长期随访研究来评估长期疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af02/10976664/be0ed525ad9f/13019_2024_2685_Fig1_HTML.jpg

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