Asimakopoulos P, Nixon I J, Shaha A R
Edinburgh Academic Department of Otolaryngology, Head and Neck Surgery, Edinburgh Cancer Centre, Edinburgh, UK.
Edinburgh Academic Department of Otolaryngology, Head and Neck Surgery, Edinburgh Cancer Centre, Edinburgh, UK.
Clin Oncol (R Coll Radiol). 2017 May;29(5):283-289. doi: 10.1016/j.clon.2017.01.001. Epub 2017 Jan 13.
Thyroid cancer metastasises to the central and lateral compartments of the neck frequently and early. The impact of nodal metastases on outcome is affected by the histological subtype of the primary tumour and the patient's age, as well as the size, number and location of those metastases. The impact of extranodal extension has recently been highlighted as an important prognosticating factor. Although clinically evident nodal disease in the lateral neck compartments has a significant impact on both survival and recurrence, microscopic metastases to the central or the lateral neck in well-differentiated thyroid cancer do not significantly affect outcome. Here we discuss the surgical management of neck metastases in well-differentiated and medullary thyroid carcinoma.
甲状腺癌经常早期转移至颈部中央和外侧区域。淋巴结转移对预后的影响受原发肿瘤的组织学亚型、患者年龄以及转移灶的大小、数量和位置影响。结外侵犯的影响最近被强调为一个重要的预后因素。尽管临床上颈部外侧区域明显的淋巴结疾病对生存和复发均有显著影响，但分化型甲状腺癌颈部中央或外侧的微小转移对预后并无显著影响。在此，我们讨论分化型甲状腺癌和髓样癌颈部转移灶的外科治疗。
