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女性酒渣鼻:病例系列。

Rhinophyma in women: a case series.

机构信息

Laser Division, Department of Dermatology, Salford Royal NHS Foundation Trust, Salford, M6 8HD, UK.

出版信息

Lasers Med Sci. 2021 Aug;36(6):1283-1287. doi: 10.1007/s10103-020-03183-z. Epub 2021 Jan 7.

DOI:10.1007/s10103-020-03183-z
PMID:33411129
Abstract

Rosacea has an overall female predominance; however, rhinophyma, a feature attributed to advanced rosacea, is exceedingly rare in females. The impact of this condition on quality of life can be profound. Multiple treatment modalities have been described. However fully ablative carbon dioxide (CO) laser for moderate-severe rhinophyma has been shown to be most effective with good cosmetic outcome and high patient satisfaction. We describe a series of 7 female patients presenting with rhinophyma to a tertiary NHS laser centre and a private dermatology clinic. A retrospective case review of rhinophyma management was performed, assessing presentation, treatments and outcomes. The mean age at presentation was 47 years (27-62 years). Three patients developed rhinophyma before the age of 30 years. One patient had severe, 2 patients had moderate and 4 patients had minor rhinophyma. Four patients underwent fractional CO laser treatment with a good cosmetic outcome. Two further patients developed scarring following fully ablative CO laser. Long-term low-dose oral isotretinoin was used in 3 patients following laser treatment, to prevent relapse. One patient solely received isotretinoin with a good outcome. In our experience, females suffering with rhinophyma presented for treatment at an early age and stage of severity. Fractional or fully ablative CO laser alone or in combination with oral isotretinoin is a very effective treatment modality.

摘要

酒渣鼻总体上以女性居多;然而,酒渣鼻鼻赘,一种归因于晚期酒渣鼻的特征,在女性中极为罕见。这种情况对生活质量的影响可能是深远的。已经描述了多种治疗方式。然而,对于中重度酒渣鼻鼻赘,完全消融的二氧化碳(CO)激光是最有效的,具有良好的美容效果和高患者满意度。我们描述了 7 名女性患者在一家 NHS 激光中心和一家私人皮肤科诊所就诊的酒渣鼻鼻赘病例。对酒渣鼻鼻赘的管理进行了回顾性病例回顾,评估了表现、治疗和结果。就诊时的平均年龄为 47 岁(27-62 岁)。有 3 名患者在 30 岁之前就出现了酒渣鼻鼻赘。1 名患者为严重程度,2 名患者为中度,4 名患者为轻度。4 名患者接受了点阵 CO 激光治疗,美容效果良好。另有 2 名患者在接受完全消融 CO 激光治疗后出现了瘢痕。3 名患者在激光治疗后长期服用低剂量口服异维 A 酸以防止复发。1 名患者仅接受异维 A 酸治疗,效果良好。根据我们的经验,患有酒渣鼻鼻赘的女性在早期和严重程度就诊。单独使用或联合口服异维 A 酸的点阵或完全消融 CO 激光是一种非常有效的治疗方式。

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Rhinophyma in women: a case series.女性酒渣鼻:病例系列。
Lasers Med Sci. 2021 Aug;36(6):1283-1287. doi: 10.1007/s10103-020-03183-z. Epub 2021 Jan 7.
2
Fractionated ablative carbon dioxide laser for the treatment of rhinophyma.分次消融二氧化碳激光治疗酒渣鼻。
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Aesthet Surg J. 2019 Mar 14;39(4):NP68-NP75. doi: 10.1093/asj/sjy234.
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Surgical treatment of rhinophyma: Retrospective monocentric study and literature review.酒渣鼻的外科治疗:回顾性单中心研究及文献复习。
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Surgical treatment of rhinophyma using carbon dioxide (CO2) laser and pulsed dye laser (PDL).使用二氧化碳(CO2)激光和脉冲染料激光(PDL)治疗酒渣鼻。
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Laser surgery in rhinophyma.酒渣鼻的激光手术
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Treatment of Rhinophyma With Fractional CO2 Laser Resurfacing in a Woman of Color: Case Report and Review of the Literature.彩色激光治疗女性酒渣鼻鼻赘:病例报告及文献复习。
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引用本文的文献

1
Efficacy and safety of non-fractional ablative carbon dioxide laser resurfacing for the treatment of rhinophyma - a retrospective cohort and questionnaires-based study.非剥脱性二氧化碳激光换肤治疗酒渣鼻的疗效和安全性——一项回顾性队列研究及问卷调查研究
Lasers Med Sci. 2025 Jun 9;40(1):261. doi: 10.1007/s10103-025-04442-7.
2
Long-term Satisfaction with CO2 Laser Treatment for Moderate to Major Rhinophyma: A Single-centre Study.二氧化碳激光治疗中重度酒渣鼻的长期满意度:一项单中心研究。
Acta Derm Venereol. 2025 Jan 3;105:adv41335. doi: 10.2340/actadv.v105.41335.

本文引用的文献

1
Procedural management of rhinophyma: A comprehensive review.酒渣鼻的手术治疗:综述
J Cosmet Dermatol. 2018 Dec;17(6):960-967. doi: 10.1111/jocd.12770. Epub 2018 Sep 17.
2
Incidence and prevalence of rosacea: a systematic review and meta-analysis.酒渣鼻的发病率和患病率:系统评价和荟萃分析。
Br J Dermatol. 2018 Aug;179(2):282-289. doi: 10.1111/bjd.16481. Epub 2018 May 31.
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Unusual features of rosacea in saudi females with dark skin.沙特黑皮肤女性酒渣鼻的异常特征。
Ochsner J. 2014 Fall;14(3):321-7.
4
Laser surgery in rhinophyma.酒渣鼻的激光手术
G Ital Dermatol Venereol. 2016 Feb;151(1):9-16. Epub 2014 Sep 18.
5
Rosacea in patients with skin of color: uncommon but not rare.有色人种患者的酒渣鼻:不常见但并非罕见。
Cutis. 2010 Aug;86(2):60-2.
6
Rosacea: 244 Tunisian cases.酒渣鼻:244例突尼斯病例。
Tunis Med. 2010 Aug;88(8):597-601.
7
Rhinophyma and coexisting occult skin cancers.酒渣鼻与并存的隐匿性皮肤癌。
Dermatol Surg. 2001 Feb;27(2):201-2. doi: 10.1046/j.1524-4725.2001.00251.x.