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女性酒渣鼻:病例系列。

Rhinophyma in women: a case series.

机构信息

Laser Division, Department of Dermatology, Salford Royal NHS Foundation Trust, Salford, M6 8HD, UK.

出版信息

Lasers Med Sci. 2021 Aug;36(6):1283-1287. doi: 10.1007/s10103-020-03183-z. Epub 2021 Jan 7.

Abstract

Rosacea has an overall female predominance; however, rhinophyma, a feature attributed to advanced rosacea, is exceedingly rare in females. The impact of this condition on quality of life can be profound. Multiple treatment modalities have been described. However fully ablative carbon dioxide (CO) laser for moderate-severe rhinophyma has been shown to be most effective with good cosmetic outcome and high patient satisfaction. We describe a series of 7 female patients presenting with rhinophyma to a tertiary NHS laser centre and a private dermatology clinic. A retrospective case review of rhinophyma management was performed, assessing presentation, treatments and outcomes. The mean age at presentation was 47 years (27-62 years). Three patients developed rhinophyma before the age of 30 years. One patient had severe, 2 patients had moderate and 4 patients had minor rhinophyma. Four patients underwent fractional CO laser treatment with a good cosmetic outcome. Two further patients developed scarring following fully ablative CO laser. Long-term low-dose oral isotretinoin was used in 3 patients following laser treatment, to prevent relapse. One patient solely received isotretinoin with a good outcome. In our experience, females suffering with rhinophyma presented for treatment at an early age and stage of severity. Fractional or fully ablative CO laser alone or in combination with oral isotretinoin is a very effective treatment modality.

摘要

酒渣鼻总体上以女性居多;然而,酒渣鼻鼻赘,一种归因于晚期酒渣鼻的特征,在女性中极为罕见。这种情况对生活质量的影响可能是深远的。已经描述了多种治疗方式。然而,对于中重度酒渣鼻鼻赘,完全消融的二氧化碳(CO)激光是最有效的,具有良好的美容效果和高患者满意度。我们描述了 7 名女性患者在一家 NHS 激光中心和一家私人皮肤科诊所就诊的酒渣鼻鼻赘病例。对酒渣鼻鼻赘的管理进行了回顾性病例回顾,评估了表现、治疗和结果。就诊时的平均年龄为 47 岁(27-62 岁)。有 3 名患者在 30 岁之前就出现了酒渣鼻鼻赘。1 名患者为严重程度,2 名患者为中度,4 名患者为轻度。4 名患者接受了点阵 CO 激光治疗,美容效果良好。另有 2 名患者在接受完全消融 CO 激光治疗后出现了瘢痕。3 名患者在激光治疗后长期服用低剂量口服异维 A 酸以防止复发。1 名患者仅接受异维 A 酸治疗,效果良好。根据我们的经验,患有酒渣鼻鼻赘的女性在早期和严重程度就诊。单独使用或联合口服异维 A 酸的点阵或完全消融 CO 激光是一种非常有效的治疗方式。

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