Department of Medicine, The Pulmonary Center, Division of Pulmonary and Critical Care Medicine, Evans Center for Implementation and Improvement Sciences, Boston University School of Medicine, Boston, MA.
Department of Biostatistics, Boston University School of Public Health, Boston, MA.
Health Serv Res. 2018 Jun;53(3):1644-1661. doi: 10.1111/1475-6773.12651. Epub 2017 Jan 18.
To determine between-hospital variation in interventions provided to patients with do not resuscitate (DNR) orders.
DATA SOURCES/SETTING: United States Agency of Healthcare Research and Quality, Healthcare Cost and Utilization Project, California State Inpatient Database.
Retrospective cohort study including hospitalized patients aged 40 and older with potential indications for invasive treatments: in-hospital cardiac arrest (indication for CPR), acute respiratory failure (mechanical ventilation), acute renal failure (hemodialysis), septic shock (central venous catheterization), and palliative care. Hierarchical logistic regression to determine associations of hospital "early" DNR rates (DNR order placed within 24 hours of admission) with utilization of invasive interventions.
DATA COLLECTION/EXTRACTION METHODS: California State Inpatient Database, year 2011.
Patients with DNR orders at high-DNR-rate hospitals were less likely to receive invasive mechanical ventilation for acute respiratory failure or hemodialysis for acute renal failure, but more likely to receive palliative care than DNR patients at low-DNR-rate hospitals. Patients without DNR orders experienced similar rates of invasive interventions regardless of hospital DNR rates.
Hospitals vary widely in the scope of invasive or organ-supporting treatments provided to patients with DNR orders.
确定有“不复苏”(DNR)医嘱的患者接受干预措施的医院间差异。
数据来源/设置:美国医疗保健研究与质量局,医疗保健成本和利用项目,加利福尼亚州住院患者数据库。
回顾性队列研究,纳入年龄在 40 岁及以上、有侵入性治疗指征的住院患者:院内心搏骤停(CPR 指征)、急性呼吸衰竭(机械通气)、急性肾衰竭(血液透析)、脓毒性休克(中心静脉置管)和姑息治疗。分层逻辑回归分析医院“早期”DNR 率(入院后 24 小时内下达 DNR 医嘱)与侵入性干预措施使用的相关性。
数据收集/提取方法:加利福尼亚州住院患者数据库,2011 年。
高 DNR 率医院的 DNR 医嘱患者接受急性呼吸衰竭侵入性机械通气或急性肾衰竭血液透析的可能性较小,但接受姑息治疗的可能性大于低 DNR 率医院的 DNR 医嘱患者。无 DNR 医嘱的患者无论医院 DNR 率如何,接受侵入性干预的几率相似。
医院在有 DNR 医嘱的患者接受的侵入性或器官支持治疗范围方面差异很大。