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本文引用的文献

1
Association of Do-Not-Resuscitate Orders and Hospital Mortality Rate Among Patients With Pneumonia.“不要复苏”医嘱与肺炎患者医院死亡率的关联
JAMA Intern Med. 2016 Jan;176(1):97-104. doi: 10.1001/jamainternmed.2015.6324.
2
When do confounding by indication and inadequate risk adjustment bias critical care studies? A simulation study.指征性混杂和风险调整不足何时会使重症监护研究产生偏差?一项模拟研究。
Crit Care. 2015 Apr 30;19(1):195. doi: 10.1186/s13054-015-0923-8.
3
Influence of institutional culture and policies on do-not-resuscitate decision making at the end of life.机构文化和政策对生命末期不复苏决策的影响。
JAMA Intern Med. 2015 May;175(5):812-9. doi: 10.1001/jamainternmed.2015.0295.
4
Variability Among US Intensive Care Units in Managing the Care of Patients Admitted With Preexisting Limits on Life-Sustaining Therapies.美国重症监护病房在管理患有预先存在的维持生命治疗限制的入院患者护理方面的差异。
JAMA Intern Med. 2015 Jun;175(6):1019-26. doi: 10.1001/jamainternmed.2015.0372.
5
Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching.两种截然不同的“不要复苏”方案,其想象空间更小:一项使用倾向评分匹配的观察性研究。
BMC Med. 2014 Aug 29;12:146. doi: 10.1186/s12916-014-0146-x.
6
Do-not-resuscitate status and observational comparative effectiveness research in patients with septic shock*.脓毒性休克患者的“不要复苏”状态与观察性比较效果研究*
Crit Care Med. 2014 Sep;42(9):2042-7. doi: 10.1097/CCM.0000000000000403.
7
Advance care planning norms may contribute to hospital variation in end-of-life ICU use: a simulation study.预先护理计划规范可能导致医院在临终重症监护病房使用方面存在差异:一项模拟研究。
Med Decis Making. 2014 May;34(4):473-84. doi: 10.1177/0272989X14522099. Epub 2014 Mar 10.
8
Variation in do-not-resuscitate orders for patients with ischemic stroke: implications for national hospital comparisons.缺血性脑卒中患者的不复苏医嘱的变化:对国家医院比较的影响。
Stroke. 2014 Mar;45(3):822-7. doi: 10.1161/STROKEAHA.113.004573. Epub 2014 Feb 12.
9
Variation of arterial and central venous catheter use in United States intensive care units.美国重症监护病房中动脉和中央静脉导管使用的变化。
Anesthesiology. 2014 Mar;120(3):650-64. doi: 10.1097/ALN.0000000000000008.
10
Rate of utilization and determinants of withdrawal of care in acute ischemic stroke treated with thrombolytics in USA.美国急性缺血性脑卒中溶栓治疗患者的治疗使用率和撤机决定因素。
Med Care. 2013 Dec;51(12):1094-100. doi: 10.1097/MLR.0b013e3182a95db4.

患者带有“不复苏”医嘱时,医院在维持生命治疗上的使用的变化。

Hospital Variation in Utilization of Life-Sustaining Treatments among Patients with Do Not Resuscitate Orders.

机构信息

Department of Medicine, The Pulmonary Center, Division of Pulmonary and Critical Care Medicine, Evans Center for Implementation and Improvement Sciences, Boston University School of Medicine, Boston, MA.

Department of Biostatistics, Boston University School of Public Health, Boston, MA.

出版信息

Health Serv Res. 2018 Jun;53(3):1644-1661. doi: 10.1111/1475-6773.12651. Epub 2017 Jan 18.

DOI:10.1111/1475-6773.12651
PMID:28097649
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5980340/
Abstract

OBJECTIVE

To determine between-hospital variation in interventions provided to patients with do not resuscitate (DNR) orders.

DATA SOURCES/SETTING: United States Agency of Healthcare Research and Quality, Healthcare Cost and Utilization Project, California State Inpatient Database.

STUDY DESIGN

Retrospective cohort study including hospitalized patients aged 40 and older with potential indications for invasive treatments: in-hospital cardiac arrest (indication for CPR), acute respiratory failure (mechanical ventilation), acute renal failure (hemodialysis), septic shock (central venous catheterization), and palliative care. Hierarchical logistic regression to determine associations of hospital "early" DNR rates (DNR order placed within 24 hours of admission) with utilization of invasive interventions.

DATA COLLECTION/EXTRACTION METHODS: California State Inpatient Database, year 2011.

PRINCIPAL FINDINGS

Patients with DNR orders at high-DNR-rate hospitals were less likely to receive invasive mechanical ventilation for acute respiratory failure or hemodialysis for acute renal failure, but more likely to receive palliative care than DNR patients at low-DNR-rate hospitals. Patients without DNR orders experienced similar rates of invasive interventions regardless of hospital DNR rates.

CONCLUSIONS

Hospitals vary widely in the scope of invasive or organ-supporting treatments provided to patients with DNR orders.

摘要

目的

确定有“不复苏”(DNR)医嘱的患者接受干预措施的医院间差异。

数据来源/设置:美国医疗保健研究与质量局,医疗保健成本和利用项目,加利福尼亚州住院患者数据库。

研究设计

回顾性队列研究,纳入年龄在 40 岁及以上、有侵入性治疗指征的住院患者:院内心搏骤停(CPR 指征)、急性呼吸衰竭(机械通气)、急性肾衰竭(血液透析)、脓毒性休克(中心静脉置管)和姑息治疗。分层逻辑回归分析医院“早期”DNR 率(入院后 24 小时内下达 DNR 医嘱)与侵入性干预措施使用的相关性。

数据收集/提取方法:加利福尼亚州住院患者数据库,2011 年。

主要发现

高 DNR 率医院的 DNR 医嘱患者接受急性呼吸衰竭侵入性机械通气或急性肾衰竭血液透析的可能性较小,但接受姑息治疗的可能性大于低 DNR 率医院的 DNR 医嘱患者。无 DNR 医嘱的患者无论医院 DNR 率如何,接受侵入性干预的几率相似。

结论

医院在有 DNR 医嘱的患者接受的侵入性或器官支持治疗范围方面差异很大。