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急诊科的死亡与不进行心肺复苏医嘱:中国大陆一项单中心三年回顾性研究

Death and do-not-resuscitate order in the emergency department: A single-center three-year retrospective study in the Chinese mainland.

作者信息

Ding Chuan-Qi, Zhang Yu-Ping, Wang Yu-Wei, Yang Min-Fei, Wang Sa, Cui Nian-Qi, Jin Jing-Fen

机构信息

Department of Nursing, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Department of Emergency Medicine, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

出版信息

World J Emerg Med. 2020;11(4):231-237. doi: 10.5847/wjem.j.1920-8642.2020.04.005.

Abstract

BACKGROUND

Consenting to do-not-resuscitate (DNR) orders is an important and complex medical decision-making process in the treatment of patients at the end-of-life in emergency departments (EDs). The DNR decision in EDs has not been extensively studied, especially in the Chinese mainland.

METHODS

This retrospective chart study of all deceased patients in the ED of a university hospital was conducted from January 2017 to December 2019. The patients with out-of-hospital cardiac arrest were excluded.

RESULTS

There were 214 patients' deaths in the ED in the three years. Among them, 132 patients were included in this study, whereas 82 with out-of-hospital cardiac arrest were excluded. There were 99 (75.0%) patients' deaths after a DNR order medical decision, 64 (64.6%) patients signed the orders within 24 hours of the ED admission, 68 (68.7%) patients died within 24 hours after signing it, and 97 (98.0%) patients had DNR signed by the family surrogates. Multivariate analysis showed that four independent factors influenced the family surrogates' decisions to sign the DNR orders: lack of referral (odds ratio [OR] 0.157, 95% confidence interval [CI] 0.047-0.529, =0.003), ED length of stay (ED LOS) ≥72 hours ( 5.889, 95% 1.290-26.885, =0.022), acute myocardial infarction (AMI) ( 0.017, 95% 0.001-0.279, =0.004), and tracheal intubation ( 0.028, 95% 0.007-0.120, <0.001).

CONCLUSIONS

In the Chinese mainland, the proportion of patients consenting for DNR order is lower than that of developed countries. The decision to sign DNR orders is mainly affected by referral, ED LOS, AMI, and trachea intubation.

摘要

背景

在急诊科(ED)对临终患者进行治疗时,同意下达“不要复苏”(DNR)医嘱是一个重要且复杂的医疗决策过程。急诊科的DNR决策尚未得到广泛研究,尤其是在中国大陆地区。

方法

本研究对一所大学医院急诊科2017年1月至2019年12月期间所有死亡患者进行回顾性病历研究。排除院外心脏骤停患者。

结果

三年间急诊科共有214例患者死亡。其中,132例患者纳入本研究,82例院外心脏骤停患者被排除。99例(75.0%)患者在下达DNR医嘱后死亡,64例(64.6%)患者在急诊科入院24小时内签署了该医嘱,68例(68.7%)患者在签署医嘱后24小时内死亡,97例(98.0%)患者的DNR医嘱由家属代理人签署。多因素分析显示,影响家属代理人签署DNR医嘱决策的四个独立因素为:缺乏转诊(比值比[OR]0.157,95%置信区间[CI]0.047 - 0.529,P = 0.003)、急诊科住院时间(ED LOS)≥72小时(OR 5.889,95%CI 1.290 - 26.885,P = 0.022)、急性心肌梗死(AMI)(OR 0.017,95%CI 0.001 - 0.279,P = 0.004)以及气管插管(OR 0.028,95%CI 0.007 - 0.120,P < 0.001)。

结论

在中国大陆地区,同意下达DNR医嘱的患者比例低于发达国家。签署DNR医嘱的决策主要受转诊、急诊科住院时间、急性心肌梗死和气管插管的影响。

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