海拔3200米处1至4个月大婴儿的血氧饱和度、周期性呼吸和睡眠呼吸暂停
Oxygen saturation, periodic breathing, and sleep apnea in infants aged 1-4 months old living at 3200 meters above sea level.
作者信息
Ucrós Santiago, Granados Claudia, Parejo Karem, Ortega Fausto, Guillén Fernando, Restrepo Sonia, Gil Fabián, Guillén Miriam
机构信息
Departamento de Pediatría, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
Departamentos de Pediatría y Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, Colombia.
出版信息
Arch Argent Pediatr. 2017 Feb 1;115(1):54-57. doi: 10.5546/aap.2017.eng.54.
OBJECTIVES
To describe, in infants aged 1-4 months old living at 3200 meters above sea level (MASL), oxygen saturation (SpO2), sleep apnea indices, and periodic breathing (PB) during sleep. Polysomnographies were done in 18 healthy infants.
RESULTS
The median SpO2 was 87%, and the median PB was 7.2% for the total sleep time. The median central sleep apnea index was 30.5/hour, which decreased to 5.4/hour once sleep apneas associated with PB were excluded. The 5th percentile for SpO2 was 76% among awake infants, and 66% among asleep infants.
CONCLUSIONS
The SpO2 was lower than that observed at sea level, whereas PB and the central sleep apnea index were higher, once sleep apneas associated with PB were excluded. The latter was similar to that observed at sea level. At 3200 MASL, different cut-off points are required for a normal SpO2, one for infants during the waking state and one for infants during sleep.
目的
描述海拔3200米处1 - 4个月大婴儿睡眠期间的血氧饱和度（SpO₂）、睡眠呼吸暂停指数和周期性呼吸（PB）情况。对18名健康婴儿进行了多导睡眠图监测。
结果
总睡眠时间中，SpO₂中位数为87%，PB中位数为7.2%。中枢性睡眠呼吸暂停指数中位数为30.5次/小时，排除与PB相关的睡眠呼吸暂停后降至5.4次/小时。清醒婴儿SpO₂的第5百分位数为76%，睡眠婴儿为66%。
结论
排除与PB相关的睡眠呼吸暂停后，SpO₂低于海平面观察值，而PB和中枢性睡眠呼吸暂停指数较高。后者与海平面观察值相似。在海拔3200米处，正常SpO₂需要不同的截断点，一个用于清醒状态的婴儿，一个用于睡眠状态的婴儿。
Zotero 插件