Labidi Jannet, Selmi Yosra, Ariba Yosra Ben, Elloumi Zied, Othmani Saleh
Department of Internal Medicine, Tunisian Military Hospital, Montfleury, Tunis, Tunisia.
Saudi J Kidney Dis Transpl. 2017 Jan-Feb;28(1):174-177. doi: 10.4103/1319-2442.198246.
Thromboembolic disease is an important and frequent complication in patients with the nephrotic syndrome (NS), and the consequences are often severe. Usually, the venous system is affected. Arterial thrombosis has rarely been reported and occurs mainly in children. We report the case of a 27-year-old man with a history of NS due to focal and segmental glomerulosclerosis resistant to steroids and cyclosporine, admitted for bilateral pain in the calves. Aortogram revealed a suspended thrombus in the abdominal aorta just below the origin of the renal arteries with embolism into the left tibioperoneal trunk and the right anterior tibial artery. Endarterectomy was performed followed by systemic heparinization with a good outcome. Arterial thrombosis is rare and must be prevented.
血栓栓塞性疾病是肾病综合征(NS)患者重要且常见的并发症,后果往往很严重。通常,静脉系统会受到影响。动脉血栓形成鲜有报道,主要发生在儿童。我们报告一例27岁男性患者,有因局灶节段性肾小球硬化导致的NS病史,对类固醇和环孢素耐药,因双侧小腿疼痛入院。主动脉造影显示肾动脉起始部下方的腹主动脉有一个悬浮血栓,并栓塞至左胫腓干和右胫前动脉。进行了动脉内膜切除术,随后全身肝素化,效果良好。动脉血栓形成罕见,必须加以预防。