Murray Kenya, Reddy Vasudha, Kornblum John S, Waechter HaeNa, Chicaiza Ludwin F, Rubinstein Inessa, Balter Sharon, Greene Sharon K, Braunstein Sarah L, Rakeman Jennifer L, Dentinger Catherine M
Emerg Infect Dis. 2017 Feb;23(2):332-335. doi: 10.3201/eid2302.161203.
Approximately 20% of Shigella isolates tested in New York City, New York, USA, during 2013-2015 displayed decreased azithromycin susceptibility. Case-patients were older and more frequently male and HIV infected than those with azithromycin-susceptible Shigella infection; 90% identified as men who have sex with men. Clinical interpretation guidelines for azithromycin resistance and outcome studies are needed.
2013年至2015年期间,在美国纽约市测试的志贺氏菌分离株中,约20%对阿奇霉素的敏感性降低。与阿奇霉素敏感的志贺氏菌感染患者相比,病例患者年龄更大,男性和艾滋病毒感染者更为常见;90%被确定为男男性行为者。需要阿奇霉素耐药性的临床解读指南和结局研究。