Silvestre Jason, Ahn Jaimo, Levin L Scott
1Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
J Bone Joint Surg Am. 2017 Jan 18;99(2):e5. doi: 10.2106/JBJS.16.00088.
The National Institutes of Health (NIH) is the largest supporter of biomedical research in the U.S., yet its contribution to orthopaedic research is poorly understood. In this study, we analyzed the portfolio of NIH funding to departments of orthopaedic surgery at U.S. medical schools.
The NIH RePORT (Research Portfolio Online Reporting Tools) database was queried for NIH grants awarded to departments of orthopaedic surgery in 2014. Funding totals were determined for award mechanisms and NIH institutes. Trends in NIH funding were determined for 2005 to 2014 and compared with total NIH extramural research funding. Funding awarded to orthopaedic surgery departments was compared with that awarded to departments of other surgical specialties in 2014. Characteristics of NIH-funded principal investigators were obtained from department web sites.
In 2014, 183 grants were awarded to 132 investigators at 44 departments of orthopaedic surgery. From 2005 to 2014, NIH funding increased 24.3%, to $54,608,264 (p = 0.030), but the rates of increase seen did not differ significantly from those of NIH extramural research funding as a whole (p = 0.141). Most (72.6%) of the NIH funding was awarded through the R01 mechanism, with a median annual award of $343,980 (interquartile range [IQR], $38,372). The majority (51.1%) of the total funds supported basic science research, followed by translational (33.0%), clinical (10.0%), and educational (5.9%) research. NIH-funded orthopaedic principal investigators were predominately scientists whose degree was a PhD (71.1%) and who were male (79.5%). Eleven NIH institutes were represented, with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) providing the preponderance (74.2%) of the funding. In 2014, orthopaedic surgery ranked below the surgical departments of general surgery, ophthalmology, obstetrics and gynecology, otolaryngology, and urology in terms of NIH funding received.
The percentage increase of NIH funding to departments of orthopaedic surgery from 2005 to 2014 was not significantly greater than that of total NIH extramural research funding. Funding levels to orthopaedic surgery departments lag behind funding to departments of other surgical disciplines. Funding levels may not match the academic potential of orthopaedic faculty, and interventions may be needed to increase NIH grant procurement.
美国国立卫生研究院(NIH)是美国生物医学研究的最大资助者,但其对骨科研究的贡献却鲜为人知。在本研究中,我们分析了NIH对美国医学院校骨科手术科室的资助情况。
查询NIH RePORT(研究项目在线报告工具)数据库,获取2014年授予骨科手术科室的NIH资助项目。确定了各资助机制和NIH研究所的资助总额。确定了2005年至2014年NIH资助的趋势,并与NIH全部院外研究资助进行比较。将授予骨科手术科室的资助与2014年授予其他外科专科科室的资助进行比较。从科室网站获取获得NIH资助的主要研究者的特征。
2014年,44个骨科手术科室的132名研究者获得了183项资助。2005年至2014年,NIH资助增加了24.3%,达到54,608,264美元(p = 0.030),但增长速度与NIH整体院外研究资助的增长速度相比无显著差异(p = 0.141)。NIH的大部分(72.6%)资助是通过R01机制授予的,年度资助中位数为343,980美元(四分位间距[IQR],38,372美元)。总资金的大部分(51.1%)用于支持基础科学研究,其次是转化研究(33.0%)、临床研究(10.0%)和教育研究(5.9%)。获得NIH资助的骨科主要研究者大多是拥有博士学位(71.1%)的男性(79.5%)。有11个NIH研究所提供了资助,其中国家关节炎、肌肉骨骼和皮肤疾病研究所(NIAMS)提供了大部分(74.2%)的资金。2014年,在获得的NIH资助方面,骨科手术科室排名低于普通外科、眼科、妇产科、耳鼻喉科和泌尿外科的外科科室。
2005年至2014年NIH对骨科手术科室资助的增长百分比并不显著高于NIH整体院外研究资助的增长百分比。骨科手术科室的资助水平落后于其他外科科室的资助水平。资助水平可能与骨科教师的学术潜力不匹配,可能需要采取干预措施来增加NIH资助的获取。