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2006年至2015年苏州地区440例儿童呼吸道腺病毒感染的流行病学分析

[Epidemiological analysis of 440 cases of respiratory adenovirus infections in children from the Suzhou area between 2006 and 2015].

作者信息

Sun Hui-Quan, Zhang Xin-Xing, Kuang Xiao-Ni, Gu Wen-Jing, Chen Zheng-Rong, Yan Yong-Dong, Wang Yu-Qing, Zhu Can-Hong, Dong He-Ting, Zhang Xue-Lan, Ji Wei

机构信息

Department of Respiratory Disease, Children's Hospital of Soochow University, Suzhou, Jiangsu 215003, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2017 Jan;19(1):34-38. doi: 10.7499/j.issn.1008-8830.2017.01.004.

Abstract

OBJECTIVE

To study the epidemiological characteristics of respiratory adenovirus (ADV) infections in children from the Suzhou area, China.

METHODS

The clinical data of ADV-positive children out of 35 529 children with respiratory tract infections who were hospitalized in the Children's Hospital of Soochow University between January 2006 and December 2015 were retrospectively studied.

RESULTS

Of the 35 529 children with respiratory tract infections, 440 (1.24%) were ADV-positive. There was no significant difference in the rate of ADV infections between boys and girls (1.18% vs 1.34%). The ADV infection rates of children at the age of <1 year old, 1-3 years old, 3-7 years old and 7-14 years old were 0.39% (71/18 002), 1.12% (103/9 191), 3.14% (201/6 398), and 3.35%( 65/1 938) respectively and the rate increased with age (P<0.01). The ADV infection rates in spring [1.85%(60/8 658)] and summer [2.20%(189/8 606)] were significantly higher than in autumn [0.30%(27/8 952)] and winter [0.69%(64/9 313)] (P<0.01).

CONCLUSIONS

The ADV infection rate is increased with age in the children from the Suzhou area, but it is not associated with gender. ADV infections are more common in spring and summer.

摘要

目的

研究中国苏州地区儿童呼吸道腺病毒(ADV)感染的流行病学特征。

方法

回顾性分析2006年1月至2015年12月在苏州大学附属儿童医院住院的35529例呼吸道感染儿童中ADV阳性患儿的临床资料。

结果

35529例呼吸道感染儿童中,440例(1.24%)为ADV阳性。男孩和女孩的ADV感染率无显著差异(1.18%对1.34%)。<1岁、1 - 3岁、3 - 7岁和7 - 14岁儿童的ADV感染率分别为0.39%(71/18002)、1.12%(103/9191)、3.14%(201/6398)和3.35%(65/1938),且感染率随年龄增长而升高(P<0.01)。春季[1.85%(60/8658)]和夏季[2.20%(189/8606)]的ADV感染率显著高于秋季[0.30%(27/8952)]和冬季[0.69%(64/9313)](P<0.01)。

结论

苏州地区儿童ADV感染率随年龄增长而升高,但与性别无关。ADV感染在春季和夏季更为常见。

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