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[2006 - 2015年北京市5岁以下儿童先天性畸形死亡率变化趋势]

[Trend of mortality of congenital malformation in children aged <5 years in Beijing, 2006-2015].

作者信息

Wang J, Li D Y, Zhang W X, Li Y C, Wang J

机构信息

Department of Children's Health Care, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Jan 10;38(1):73-76. doi: 10.3760/cma.j.issn.0254-6450.2017.01.014.

Abstract

To investigate the change in mortality of congenital malformation in children aged <5 years in Beijing from 2006 to 2015. Using the death surveillance data in children aged <5 years in Beijing from 2006 to 2015, which was collected from the real-time surveillance network, we calculated the area and age distributions of the mortality of congenital malformation in children aged <5 years in Beijing. Meanwhile, the variations of age, time and space in the causes of deaths were discussed. The mortality rate of congenital malformation in the children s decreased from 1.909‰ in 2006 to 0.703‰ in 2015, the decrease rate was 63.17. The decrease rate was highest in neonates (71.50) ((2)=57.993, <0.01). Expect urban area ((2)=3.384, >0.05), the mortality rates of congenital malformation in the children showed a downward trend in outer suburban area and suburban area ((2) =40.637 and 50.646, <0.01). The proportion of the children died of congenital malformation decreased from 32.97 in 2006 to 23.24 in 2015, which mainly occurred in infancy and neonatal period ((2)=9.395 and 4.354, <0.05). The constituent ratios of the children died of neural tube defects, respiratory system abnormalities and other abnormalities decreased significantly ((2)=13.478, 7.358, 7.912 and 10.074, <0.01). The constituent ratios of children died of chromosomal abnormality, multiple malformations and digestive tract abnormality didn' t decreased significantly (>0.05). In the leading causes of deaths from congenital malformation, the mortality of congenital heart disease, neural tube defects and digestive tract atresia decreased obviously ((2)=70.868, 18.431 and 9.225, <0.01), except biliary atresia ((2)= 1.407, >0.05). There was an obvious area specific difference between the deaths of congenital heart disease and the deaths of neural tube defects, the mortality was higher in outer suburbs than in suburban and urban area ((2)=45.783 and 6.649, <0.05). Although the mortality rate of children with congenital malformation in Beijing has declined year by year, it is still the main cause of deaths in children under 5 years old, and the prevention and control of related diseases should be strengthened.

摘要

调查2006年至2015年北京市5岁以下儿童先天性畸形死亡率的变化情况。利用2006年至2015年北京市5岁以下儿童死亡监测数据(该数据来自实时监测网络),我们计算了北京市5岁以下儿童先天性畸形死亡率的地区和年龄分布。同时,探讨了死亡原因在年龄、时间和空间上的变化情况。儿童先天性畸形死亡率从2006年的1.909‰降至2015年的0.703‰,下降率为63.17%。新生儿下降率最高(71.50%)(χ²=57.993,P<0.01)。除城区外(χ²=3.384,P>0.05),远郊区和近郊区儿童先天性畸形死亡率呈下降趋势(χ²分别为40.637和50.646,P<0.01)。死于先天性畸形的儿童比例从2006年的32.97%降至2015年的23.24%,主要发生在婴儿期和新生儿期(χ²分别为9.395和4.354,P<0.05)。死于神经管缺陷、呼吸系统异常及其他异常的儿童构成比显著下降(χ²分别为13.478、7.358、7.912和10.074,P<0.01)。死于染色体异常、多发畸形及消化道异常的儿童构成比无显著下降(P>0.05)。在先天性畸形主要死因中,先天性心脏病、神经管缺陷及消化道闭锁死亡率明显下降(χ²分别为70.868、18.431和9.225,P<0.01),除胆道闭锁外(χ²=1.407,P>0.05)。先天性心脏病死亡与神经管缺陷死亡存在明显的地区差异,远郊区死亡率高于近郊区和城区(χ²分别为45.783和6.649,P<0.05)。虽然北京市先天性畸形儿童死亡率逐年下降,但仍是5岁以下儿童主要死因,应加强相关疾病的防控。

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