Fujino Minoru, Mori Daisuke, Akashi Michiaki, Yamamoto Hidetaka, Aibe Hitoshi, Matake Kunishige, Shirahane Kengo
Department of Breast Surgery, Saga Medical Center Koseikan, Saga, Japan.
Department of Pathology, Saga Medical Center Koseikan, Saga, Japan.
Case Rep Oncol. 2016 Nov 29;9(3):806-814. doi: 10.1159/000452792. eCollection 2016 Sep-Dec.
A 71-year-old woman, previously treated for malignant lymphoma, was admitted to our hospital with a tumor in the right breast. The tumor size was 2.0 cm in diameter, and the borderline was unclear. The core needle biopsy material revealed an invasive adenocarcinoma with metaplastic change. Right mastectomy and sentinel lymph node biopsy was performed. Histologically, the tumor was composed of mucus-secreting, epidermoid, and intermediate cells. These findings confirmed the diagnosis as mucoepidermoid carcinoma (MEC) of the breast. MEC is more frequently observed in the salivary glands and occurs rarely in the breast, with an incidence of approximately 0.3% of all breast cancers. Because of the rarity of the disease, the clinicopathological features and clinical outcome have not been fully investigated. The relationship between MEC of the breast and lymphoma are unclear. Here we report a rare case of MEC of the breast.
一名71岁女性，曾接受过恶性淋巴瘤治疗，因右乳出现肿瘤而入住我院。肿瘤直径为2.0厘米，边界不清。粗针活检材料显示为伴有化生改变的浸润性腺癌。行右乳房切除术及前哨淋巴结活检。组织学检查显示，肿瘤由分泌黏液的细胞、表皮样细胞和中间细胞组成。这些发现确诊为乳腺黏液表皮样癌（MEC）。MEC在唾液腺中更常见，在乳腺中很少发生，约占所有乳腺癌的0.3%。由于该疾病罕见，其临床病理特征和临床结局尚未得到充分研究。乳腺MEC与淋巴瘤之间的关系尚不清楚。在此，我们报告一例罕见的乳腺MEC病例。
